Agent Name

Amines, C12-14-tert-alkyl

Alternative Name

Primene 81-R

CAS Number




Major Category

Nitrogen Compounds


t-Alkyl (C12-C14) primary amines; Primene 81-R; [ChemIDplus] Primene 81-R Amines; [EPA ChAMP: Initial Risk-Based Prioritization] Amines, C12-C14 tert alkyl; [ToxPlanet: ECHA REACH Registrations] C12-C14 t-alkyl amines and related reaction products; [Rohm and Haas MSDS] UN2922


Amines, Aliphatic


Light colored liquid with an odor of amines; [Rohm and Haas MSDS]


Used as a fuel, lubricant additive, in surfactants, dyes, refinery processing, and metalworking fluids; [EPA ChAMP: Initial Risk-Based Prioritization] Used to formulate fuels-fuel additives, lubricants-greases, metal surface treatment products (including those for galvanizing and electroplating), inks-toners, hydraulic fluids, processing aids (i.e. pH regulators, flocculants, and precipitants), metalworking fluids, and textile dyes-finishes-impregnating products; [ToxPlanet: ECHA REACH Registrations]


Corrosive to skin and eyes in rabbits; Delayed contact hypersensitivity but no contact sensitization observed in Buehler tests of guinea pigs; Histopathological changes of the nasal cavity and respiratory tract observed in 4-week inhalation study of rats at concentrations of 129 mg/m3 and above; Developmental toxicity (in the presence of parental toxicity) noted in oral but not dermal studies of rats; [EPA ChAMP: Qualitative Screening-Level Risk Characterization] Causes burns; May cause skin sensitization; Harmful by ingestion; Highly toxic by inhalation; Toxic by skin absorption; [ToxPlanet: ECHA REACH Registrations] Causes burns; A respiratory tract irritant; May cause skin sensitization; Harmful by ingestion and skin absorption; Prolonged or repeated exposure may cause adrenal and reproductive effects; [Rohm and Haas MSDS] See "tert-Butylamine."

Exposure Assessment
Vapor Pressure

0.36 mm Hg

Lethal Concentration

LC50 (rat) = 157 ppm/4hr

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Corrosive liquid, toxic, n.o.s."

Adverse Effects
Skin Sensitizer


Toxic Pneumonitis



Skin Burns

Links to Other NLM Databases
Toxicity Information


Chemical Information

Search ChemIDplus

Related Information in HazMap

Occupational diseases associated with exposure to this agent:


Industrial Processes with risk of exposure: