Agent Name

Chromium dioxide

CAS Number

12018-01-8

Formula

Cr-O2

Major Category

Metals

Synonyms

Accrox C; Accrox R; Chromium dioxide (CrO2); Chromium oxide (CrO2); Chromium(IV) oxide; Magtrieve; [ChemIDplus] Chromium [VI] dioxide; [IARC]

Category

Chromium Compounds, Inorganic

Description

Brown to black powder; [HSDB] The needle-like crystals are strongly magnetic; [Hawley]

Sources/Uses

Used in magnetic tapes for recording, in ceramics, as a catalyst, and in special polishing operations; [HSDB]

Comments

CrVI compounds are irritants, sensitizers, and may be corrosive to the skin. CrVI compounds are respiratory tract irritants and may cause pulmonary sensitization. CrVI may cause acute tubular necrosis and liver injury. [ATSDR Case Studies] "There is sufficient evidence in humans for the carcinogenicity of chromium [VI] compounds as encountered in the chromate production, chromate pigment production and chromium plating industries." [IARC] See "Chromium" and linked occupational diseases.

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

0.05 mg/m3, as Cr

PEL (OSHA)

0.005 mg/m3, as Cr(VI)

Explanatory Notes

mp = 300 deg C, minus oxygen; [HSDB]

Adverse Effects
Skin Sensitizer

Yes

Asthma

Yes

Hepatotoxin

Hepatotoxin, Secondary

Nephrotoxin

Yes

Dermatotoxin

Skin Burns

IARC Carcinogen

Known Carcinogen

NTP Carcinogen

Human Carcinogen

ACGIH Carcinogen

Confirmed Human

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: