Agent Name

Urethane

Alternative Name

Carbamic acid, ethyl ester

CAS Number

51-79-6

Formula

C3-H7-N-O2

Major Category

Other Classes

Synonyms

Carbamic acid, ethyl ester; A 11032; Aethylcarbamat [German]; Aethylurethan [German]; Carbamidsaeure-aethylester [German]; Estane 5703; Ethyl carbamate; Ethyl urethan; Ethyl urethane; Ethylcarbamate; Ethylester kyseliny karbaminove [Czech]; Ethylurethan; Ethylurethane; Leucethane; O-Ethylurethane; Pracarbamin; Pracarbamine; U-Compound; Uretan etylowy [Polish]; Uretano [DCIT]; Urethan; Urethanum [INN-Latin]; X 41; Carbamic acid, ethyl ester; [ChemIDplus]

Category

Carbamic Acid Esters

Description

Water-soluble crystals or white powder; [CAMEO]

Sources/Uses

Used as an antineoplastic agent, veterinary anesthetic, and chemical intermediate; [ChemIDplus] Used as an intermediate, amino resin modifier, solvent, and animal anesthetic; Occurs naturally in fermented wines and foods; [Merck Index]

Comments

Harmful by inhalation or skin absorption and toxic by ingestion; Toxic to the liver; May cause CNS depression; [CAMEO] Inhalation can cause unconsciousness; [ICSC] Induces genetic damage in germ cells of humans or animals (3A); [MAK]

Exposure Assessment
Vapor Pressure

0.36 mm Hg

Explanatory Notes

mp = 118-122 deg F; bp = 360-363 deg F at 760 mm Hg; VP = 5.0 mm Hg at 150.4 deg F; [CAMEO] VP = 48 Pa (0.36 mm Hg) at 25 deg C; [ICSC]

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Reproductive Toxin

Yes

IARC Carcinogen

Probable Carcinogen

NTP Carcinogen

Anticipated Human Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: