Agent Name

Halothane

CAS Number

151-67-7

Formula

C2-H-Br-Cl-F3

Major Category

Other Uses

Synonyms

(+-)-2-Bromo-2-chloro-1,1,1-trifluoroethane; 1,1,1-Trifluoro-2-bromo-2-chloroethane; 1,1,1-Trifluoro-2-chloro-2-bromoethane; 1-Bromo-1-chloro-2,2,2-trifluoroethane; 2,2,2-Trifluoro-1-chloro-1-bromoethane; 2-Brom-2-chlor-1,1,1-trifluorethan; 2-Bromo-2-chloro-1,1,1-trifluoroethane; Alotano; Alotano [DCIT]; Anestan; Bromchlortrifluoraethanum; Bromochlorotrifluoroethane; Chalothane; Ethane, 1-bromo-1-chloro-2,2,2-trifluoro-; Ethane, 2-bromo-2-chloro-1,1,1-trifluoro-, (+-)-; Fluktan; Fluorotane; Fluothane; Freon 123B1; Ftorotan; Ftorotan [Russian]; Ftuorotan; Halan; Halotan; Halotano; Halotano [INN-Spanish]; Halothan; Halothane; Halothanum [INN-Latin]; Halsan; Narcotan; Narcotane; Narcotann NE-spofa [Russian]; Narkotan; Phthorothanum; Rhodialothan; [ChemIDplus] UN8027

Category

Waste Anesthetic Gases

Description

Clear, colorless liquid with a sweetish, pleasant odor; inhalation anesthetic; [NIOSH]

Sources/Uses

Used as an anesthetic; [HSDB]

Comments

See "WASTE ANESTHETIC GASES" Halothane is in the list of "Some volatile substances which may be abused by inhalation" published on the web site of the U.N. International Drug Control Programme, indicating its potential to cause narcosis in workers. [Reference #1] Inhalation of high concentrations can cause CNS depression, cardiac arrhythmias, and liver injury; [ICSC]

Reference Link

Volatile Substance Abuse

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

50 ppm

MAK

5 ppm

Vapor Pressure

302 mm Hg

Lethal Concentration

LC50 (rat) = 29,000 ppm

Explanatory Notes

NIOSH Rel = 60 min. ceiling of 2 ppm;

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Reproductive Toxin

Yes

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Other Information

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