Agent Name

Acridine orange

CAS Number

65-61-2

Formula

C17-H19-N3.Cl-H

Major Category

Dyes

Synonyms

3,6-Acridinediamine, N,N,N',N'-tetramethyl-, monohydrochloride; 3,6-Bis(dimethylamino)acridine hydrochloride; Acridine Orange; Acridine Orange N; Acridine Orange NO; Acridine Orange NS; Acridine Orange R; Basic Orange 14; Basic Orange 3RN; C.I. 46005; C.I. Basic Orange 14; Rhoduline Orange; Rhoduline Orange NO; [ChemIDplus]

Category

Acridine Dyes

Sources/Uses

"N,N,N',N'-Tetramethyl-3,6-acridinediamine, monohydrochloride. Cationic cytochemical stain specific for cell nuclei, especially DNA. It is used as a supravital stain and in fluorescence cytochemistry. It may cause mutations in microorganisms." [ChemIDplus]

Comments

Has mutagenic potential that is enhanced by light; Acridine dyes are derived from 3,6-diaminoacridine, 9-(4'-aminophenyl)-3-aminoacridine, and 9-(4'-aminophenyl)-3,6-diaminoacridine. One of the oldest acridine dyes is chrysaniline. Acridine dyes have low light fastness. In the past they were used for printing on cotton. Currently, they are not commercially important. [Ullmann] See "Acridine."

Adverse Effects
IARC Carcinogen

Not Classifiable

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Other Information

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