Agent Name

Bis(triphenylphosphine)nickel(II) chloride

CAS Number

14264-16-5

Formula

C36-H30-Cl2-Ni-P2

Major Category

Metals

Synonyms

Bis(triphenylphosphine)dichloronickel; Bis(triphenylphosphine)nickel dichloride; Dichlorobis(triphenylphosphine)nickel; Nickel, bis(triphenylphosphine)dichloro-; Nickel, dichlorobis(triphenylphosphine)-; Phosphine, tributyl-, compd. with nickelchloride (2:1); [ChemIDplus]

Category

Metals, Organic Compounds

Description

Solid; [Sigma-Aldrich MSDS]

Sources/Uses

Used as a solvent in the production of active pharmaceutical ingredients (API); [ToxPlanet: ECHA REACH Registrations]

Comments

Intravenous LD50 (mouse) = 56 mg/kg; [RTECS] May cause skin sensitization; [ToxPlanet: ECHA REACH Registrations] May cause skin sensitization; Possible carcinogen; [Sigma-Aldrich MSDS] See "Nickel" and linked occupational diseases.

Exposure Assessment
PEL (OSHA)

1 mg/m3, as Ni

Adverse Effects
Skin Sensitizer

Yes

Asthma

Yes

IARC Carcinogen

Known Carcinogen

NTP Carcinogen

Human Carcinogen

Links to Other NLM Databases
Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: