Agent Name

Mandelonitrile

CAS Number

532-28-5

Formula

C8-H7-N-O

Major Category

Nitrogen Compounds

Synonyms

alpha-Hydroxybenzeneacetonitrile; Acetonitrile, hydroxyphenyl-; Amygdalonitrile; Benzaldehyde cyanohydrin; Benzaldehydkyanhydrin [Czech]; Glycolonitrile, phenyl-; Mandelic acid nitrile; Nitril kyseliny mandlove [Czech]; Phenylglycolonitrile; alpha-Hydroxybenzeneacetonitrile; Benzeneacetonitrile, alpha-hydroxy-; [ChemIDplus] alpha-Cyanobenzyl alcohol; alpha-Hydroxyphenylacetonitrile; Benzaldehyde, cyanohydrin; 2-Hydroxy-2-phenylacetonitrile; Hydroxyphenylacetonitrile; [CAMEO] UN3276

Category

Nitriles

Description

Reddish-brown liquid; [CAMEO] Yellow to red-brown liquid; [Alfa Aesar MSDS]

Sources/Uses

Used to make bitter almond water; [Merck Index] Used in organic synthesis; [NTP] "Mandelonitrile, with the formula C6H5CH(OH)CN, occurs in small amounts in the pits of some fruits. Related cyanogenic glycosides are known, such as amygdalin." [Wikipedia]

Comments

Mortality and corneal opacity observed immediately following application to the eye of a rabbit; [ToxPlanet: EPA - TSCATS] A severe eye irritant; Causes spastic paralysis and respiratory depression in subcutaneous lethal-dose studies of rabbits and frogs; Intravenous LD50 (mouse) = 5.6 mg/kg; [RTECS] An irritant that may cause serious eye injury; Toxic by ingestion; [Alfa Aesar MSDS] See "NITRILES." See "m-Phthalodinitrile."

Exposure Assessment
TIH

Yes

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Nitriles, liquid, toxic, n.o.s."

Adverse Effects
Other Poison

Chemical Asphyxiant

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.