Agent Name

m-Anisidine

CAS Number

536-90-3

Formula

C7-H9-N-O

Major Category

Nitrogen Compounds

Synonyms

3-Anisidine; 1-Amino-3-methoxybenzene; 3-Aminoanisole; 3-Methoxyaniline; 3-Methoxybenzenamine; m-Aminoanisole; m-Anisylamine; m-Methoxyaniline; Benzenamine, 3-methoxy-; [ChemIDplus] 3-Aminophenol methyl ether; [ICSC] m-Aminomethoxybenzene; 3-Methoxybenzeneamine; 3-Methoxyphenylamine; [CAMEO] UN2431

Category

Amines, Aromatic

Description

Light yellow liquid; [Merck Index] Dark red liquid; [Sigma-Aldrich MSDS]

Sources/Uses

Used to make azo dyes; [Merck Index] Also used to make pharmaceuticals and textile-processing chemicals; [HSDB]

Comments

May induce methemoglobinemia; [ICSC] A 42-day oral study of rats demonstrated effects suggestive of adverse effects on the hematopoietic system, liver, and kidney (LOAEL of 12 mg/kg/day); No parturition and decreased gestation index at 300 mg/kg/day (possible lethality in early fetal stages); [OECD SIDS] A strong skin, eye, and mucous membrane irritant; [HSDB] A skin and strong eye irritant; May induce methemoglobinemia; Harmful by ingestion; [Sigma-Aldrich MSDS] See "o-Anisidine" and "p-Anisidine."

Exposure Assessment
Vapor Pressure

0.07 mm Hg

Adverse Effects
Methemoglobinemia

Methemoglobinemia, Secondary

Links to Other NLM Databases
Health Studies

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