Agent Name

m-Toluic acid

CAS Number

99-04-7

Formula

C8-H8-O2

Major Category

Other Classes

Synonyms

3-Toluic acid; 3-Methylbenzoic acid; beta-Methylbenzoic acid; m-Methylbenzoic acid; m-Toluylic acid; meta-Toluic acid; Benzoic acid, 3-methyl-; [ChemIDplus] MTA; m-Methylbenzoate; [Reference #1]

Category

Organic Acids

Description

White to yellowish or yellow solid with a sweet floral odor; [CAMEO] Light yellow powder; [Sigma-Aldrich MSDS]

Sources/Uses

Used primarily as an intermediate for the insect repellent DEET; About 1% used to make a plastic stabilizer; [Reference #1]

Comments

Causes muscle weakness, respiratory depression, and nausea in oral lethal-dose studies of mice; [RTECS] Not considered a skin irritant; Potential sensitizer; [Reference #1] Oral repeated dose study of rats produced changes in hematology and increased relative pituitary weight in males and increased relative and absolute liver weights (with corresponding histopathology) in females at 1,000 mg/mg/day (histological changes also observed in 300 mg/kg/day females); No evidence of reproductive or developmental toxicity; [Reference #1] Harmful by ingestion; [Sigma-Aldrich MSDS] Search for (99-04-7[EC/RN Number]) AND (allergic OR dermatitis OR sensitizer OR sensitization): no results; [PubMed]

Reference Link

OECD SIDS: m-Toluic acid - 2003

Exposure Assessment
Vapor Pressure

0.00014 mm Hg

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.