Agent Name

N-Nitroso-2,6-dimethylmorpholine

CAS Number

1456-28-6

Formula

C6-H12-N2-O2

Major Category

Nitrogen Compounds

Synonyms

2,6-Dimethyl-N-nitroso-morpholine; 2,6-Dimethyl-N-nitrosomorpholine; 2,6-Dimethylnitrosomorpholine; Dimethylnitrosomorpholine; DMNM; Morpholine, 2,6-dimethyl-N-nitroso-; Nitroso-2,6-dimethylmorpholine; 2,6-Dimethyl-4-nitrosomorpholine; Morpholine, 2,6-dimethyl-4-nitroso-; [ChemIDplus]

Category

Nitrosamines

Sources/Uses

Formed from the nitrosation of 2,6-dimethylmorpholine (dehydration product of bis(2-hydroxypropyl)amine); Both can be found in industrial oils; Used in carcinogenesis research; [ToxPlanet: Cal/EPA: OEHHA]

Comments

Increases tumor incidence in experimental animals by various routes of exposure; [ToxPlanet: Cal/EPA: OEHHA] Causes other liver changes, chronic pulmonary edema, and ulceration of the stomach in oral lethal-dose studies of guinea pigs; [RTECS] See "Nitrosamines." See "N-Nitrosomorpholine."

Exposure Assessment
Vapor Pressure

0.02 mm Hg

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

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