Agent Name

Diatrizoate sodium

CAS Number

737-31-5

Formula

C11-H9-I3-N2-O4.Na

Major Category

Other Classes

Synonyms

Histopaque; 3,5-Diacetamido-2,4,6-triiodobenzoic acid, sodium salt; 3,5-Diacetylamino-2,4,6-trijodbenzosaeure natrium [German]; Amidotrizoate de sodium [INN-French]; Amidotrizoato sodico [INN-Spanish]; Benzoic acid, 3,5-diacetamido-2,4,6-triiodo-, sodium salt; Conray 35; Diatrizoate sodium salt; Diatrizoic acid sodium salt; Hpaque - cysto; Hypaque; Hypaque 50; Hypaque Cysto; Hypaque sodium; Hypaque sodium 20%; Hypaque-DIU; MD 50; MD-50; Monosodium 3,5-diacetamido-2,4,6-triiodobenzoate; Natrii amidotrizoas [INN-Latin]; Radioselectan; Renografin 76 Injectable (Veterinary); Sodium 3,5-diacetamido-2,4,6-triiodobenzoate; Sodium amidotrizoate; Sodium Amidotrizoate (INN); Sodium diacetyldiaminetriiodobenzoate; Sodium diatrizoate; Sodium Diatrizoate (BAN); Triombrin; Triombrine; Urografic acid, sodium salt; Urovist 300; Urovist Sodium; Urovist Sodium 300; Vascoray; WIN 8308-3; Benzoic acid, 3,5-bis(acetylamino)-2,4,6-triiodo-, monosodium salt; Benzoic acid, 3,5-diacetamido-2,4,6-triiodo-, monosodium salt; [ChemIDplus]

Category

Other Organic Compounds

Description

Solid; [Merck Index] White powder; [Sigma-Aldrich MSDS]

Sources/Uses

Used as a density gradient reagent for blood cell separation and radiopaque diagnostic aid; [Merck Index] "Diatrizoic acid (or its anionic form, diatrizoate), also known as amidotrizoic acid, or 3,5-diacetamido-2,4,6-triiodobenzoic acid, is a radiocontrast agent containing iodine. Trade names include Hypaque, Gastrografin and Urografin, the latter being a combination of the sodium and meglumine salts." [Wikipedia]

Comments

Causes convulsions and cyanosis in oral and intraperitoneal lethal-dose studies of mice and rats; [RTECS] May cause skin and respiratory sensitization; Targets the blood; [Sigma-Aldrich MSDS] Search for (737-31-5[EC/RN Number]) AND (allergic OR dermatitis OR sensitizer OR sensitization OR asthma): no results; [PubMed]

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