Agent Name

tert-Butyldimethylchlorosilane

CAS Number

18162-48-6

Formula

C6-H15-Cl-Si

Major Category

Toxic Gases & Vapors

Synonyms

t-Butyldimethylchlorosilane; Chloro-tert-butyldimethylsilane; TBDMS chloride; tert-Butylchlorodimethylsilane; tert-Butyldimethylsilyl chloride; Chloro(1,1-dimethylethyl)dimethylsilane; Silane, chloro(1,1-dimethylethyl)dimethyl-; Silane, chloro-tert-butyldimethyl- (8CI); Silane, t-butylchlorodimethyl-; [ChemIDplus] TBDMS-Cl; TBS-Cl; t-BuMe2SiCl; [Merck Index] UN2925

Category

Chlorosilanes

Description

White hygroscopic solid; [Merck Index] White crystals with a pungent odor; [Alfa Aesar MSDS]

Sources/Uses

Used as a reagent; [Merck Index]

Comments

Causes decreased immune response in intraperitoneal lethal-dose studies of mice (LDLo = 1,000 mg/kg); [RTECS] Corrosive; [Merck Index] Reacts with water producing hydrochloric acid; Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract; [Alfa Aesar MSDS] See "Chlorotrimethylsilane."

Exposure Assessment
Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Flammable solid, corrosive, organic, n.o.s."

Adverse Effects
Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Other Information

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