Agent Name

Dimethylamine

CAS Number

124-40-3

Formula

C2-H7-N

Major Category

Nitrogen Compounds

Synonyms

Dimethylamine; Dimethylamine (anhydrous); Methanamine, N-methyl-; N,N-Dimethylamine; N-Methylmethanamine; [ChemIDplus] UN1032; UN1160

Category

Amines, Aliphatic

Description

Colorless gas with an ammonia- or fish-like odor; Note: A liquid below 44 degrees F. Shipped as a liquefied compressed gas; [NIOSH]

Sources/Uses

Used as an accelerator in the manufacturing of rubber, detergents, and pesticides; Used in leather tanning; Urinary excretion in humans increased after eating certain fish, meat, dairy, and grains containing DMA; [ACGIH] Used in electroplating, epoxy resin curing, textile manufacturing, photographic processing, hide dehairing, and pharmaceutical production; [HSDB]

Comments

Liquid causes first degree burns on short exposure; [CHRIS] Corrosive to skin; [Quick CPC] Concentrations above 5420 ppm are lethal to mice with pulmonary hemorrhages and peripheral emphysema on pathological examination. Dermal sensitizer; [ACGIH] Pulmonary edema may result from inhalation of high concentrations. [NJ-HSFS] May cause permanent eye injury; Transient visual effects ("blue haze" or "halo vision") occur at low concentrations; [CHEMINFO] Animals suffer liver injury in high-dose experiments. [HSDB]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

5 ppm

STEL (ACGIH)

15 ppm

PEL (OSHA)

10 ppm

MAK

2 ppm

WEEL

1 ppm

IDLH (NIOSH)

500 ppm

Excerpts from Documentation for IDLHs

Basis for revised IDLH: The revised IDLH for dimethylamine is 500 ppm based on acute inhalation toxicity data in animals [Steinhagen et al. 1982].

Vapor Pressure

1297 mm Hg

Odor Threshold Low

0.00076 ppm

Odor Threshold High

1.6 ppm

RD50

511 ppm

Lethal Concentration

LC50 (rat) = 4,540 ppm/6H

Explanatory Notes

Odor threshold from AIHA; The Guide from the Emergency Response Guidebook is for anhydrous dimethylamine. Flash point = 20 deg F; The AIHA WEEL = 1 ppm with a STEL of 3 ppm;

Reference Link

ICSC: Dimethylamine

Flammability (NFPA)

4: Burns readily

Adverse Effects
Skin Sensitizer

Yes

Toxic Pneumonitis

Yes

Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
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Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: