Agent Name

Trimethylamine

CAS Number

75-50-3

Formula

C3-H9-N

Major Category

Nitrogen Compounds

Synonyms

Dimethylmethaneamine; Methanamine, N,N-dimethyl-; N,N-Dimethylmethanamine; N-Trimethylamine; [ChemIDplus] UN1083; UN1297

Category

Amines, Aliphatic

Description

Colorless gas with a fishy, amine odor; Note: A liquid below 37 degrees F. Shipped as a liquefied compressed gas; [NIOSH]

Sources/Uses

Used in organic synthesis, as an insect attractant, and as a warning gas in natural gas; [Merck Index] Also used as a flotation agent; It is a natural decomposition product of plants and animals; [ACGIH]

Comments

Has a highly offensive odor at < 1 ppm; "TLV Basis" is irritation (skin, eyes, and upper respiratory tract); [ACGIH] Liquid causes first degree burns on short exposure. [CHRIS ] Corrosive to skin; [Quick CPC] Possible frostbite from contact with liquid; [NIOSH] May cause permanent eye injury; Transient visual effects ("blue haze" or "halo vision") occur at low concentrations; [CHEMINFO] May cause respiratory tract irritation and pulmonary edema; [ICSC]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

5 ppm

STEL (ACGIH)

15 ppm

MAK

2 ppm

WEEL

1 ppm

Odor Threshold Low

0.0002 ppm

Odor Threshold High

0.00087 ppm

Lethal Concentration

LCLo (rat) = 3,500 ppm/4h

Explanatory Notes

Odor threshold from AIHA; The Guide from the Emergency Response Guidebook is for anhydrous trimethylamine.

Reference Link

ICSC: Trimethylamine

Flammability (NFPA)

4: Burns readily

Adverse Effects
Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: