Agent Name

Triethylamine

CAS Number

121-44-8

Formula

C6-H15-N

Major Category

Nitrogen Compounds

Synonyms

(Diethylamino)ethane; Ethanamine, N,N-diethyl-; N,N-Diethylethanamine; TEA; TEN; Triaethylamin [German]; Triethylamine; Trietilamina [Italian; [ChemIDplus] UN1296

Category

Amines, Aliphatic

Description

Colorless liquid with a strong, ammonia-like odor; [NIOSH]

Sources/Uses

Used as a catalyst for polyurethane foams, an accelerator for rubber, and a curing agent for amino and epoxy resins; (HSDB) Used as an accelerator in photography development; [ILO Encyclo: Amines, Aliphatic] Used to make quaternary ammonium compounds and as a catalyst to make sand-based cores and molds; [ACGIH]

Comments

TLV Basis is visual impairment and upper respiratory tract irritation; Transient visual disturbances with blurring and halo vision are reported to occur at 3 to 4 ppm but not at 1 to 1.25 ppm. Mice that inhaled lethal concentrations had respiratory irritation, tremors, and convulsions. [ACGIH] Liquid causes first degree burns on short exposure; [CHRIS] Corrosive to skin; [Quick CPC] Short-term exposure at high concentrations may cause pulmonary edema. [ICSC] May cause permanent eye injury; Transient visual effects ("blue haze" or "halo vision") occur at low concentrations; [CHEMINFO] Experimental animals exposed repeatedly to 100 ppm show evidence of liver, kidney, lung, and heart damage. [HSDB] A corrosive substance that can cause pulmonary edema; [ICSC]

Exposure Assessment
Skin Designation (ACGIH)

Yes

TLV (ACGIH)

0.5 ppm

STEL (ACGIH)

1 ppm

PEL (OSHA)

25 ppm

MAK

1 ppm

IDLH (NIOSH)

200 ppm

Excerpts from Documentation for IDLHs

Basis for original (SCP) IDLH: The chosen IDLH is based on the UCC [1970] report that a 4hour exposure to 1,000 ppm killed 1 of 6 rats. . . . Human data: None relevant for use in determining the revised IDLH.

Vapor Pressure

54 mm Hg

Odor Threshold Low

0.1 ppm

Odor Threshold High

0.65 ppm

RD50

184 ppm

Lethal Concentration

LCLo (rat) = 1,000 ppm/4 hr

Explanatory Notes

Detection odor threshold from AIHA (mean = 0.25 ppm); Flash point = -7 deg C;

Reference Link

ICSC: Triethylamine

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Toxic Pneumonitis

Yes

Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Processes

Industrial Processes with risk of exposure: