Agent Name

n-Butylamine

CAS Number

109-73-9

Formula

C4-H11-N

Major Category

Nitrogen Compounds

Synonyms

1-Amino-butaan [Dutch]; 1-Aminobutan [German]; 1-Aminobutane; 1-Butanamine; Butylamine; Mono-n-butylamine; Monobutilamina [Romanian]; Monobutylamine; Norvalamine; n-Butilamina [Italian]; n-Butylamin [German]; n-Butylamine; [ChemIDplus] UN1125

Category

Amines, Aliphatic

Description

Colorless liquid with a fishy ammonia-like odor; [NIOSH]

Sources/Uses

Used as an intermediate in the synthesis of dyes, drugs, rubber additives, emulsifiers, tanning agents, and insecticides; also used as a vulcanizing accelerator for rubber and as a curing agent for polymers; [NIOSH Guidelines for Chemical Hazards]

Comments

Liquid will burn skin; [CHRIS] Highly corrosive to skin; [Quick CPC] n-Butylamine can cause severe skin and eye burns as well as respiratory tract irritation and, potentially, pulmonary edema. [ACGIH] A corrosive substance that can cause pulmonary edema; [ICSC]

Exposure Assessment
Skin Designation (ACGIH)

Yes

Ceiling (ACGIH)

5 ppm

PEL (OSHA)

Ceiling(OSHA) = 5 ppm

MAK

2 ppm

IDLH (NIOSH)

300 ppm

Excerpts from Documentation for IDLHs

Other animal data: Rats have survived a 4hour exposure to 2,000 ppm [Cheever et al. 1982]. It has been stated that butylamine is more than twice as toxic as ethylamine by the respiratory route [ACGIH 1991].

Vapor Pressure

92.9 mm Hg

Odor Threshold Low

0.08 ppm

Lethal Concentration

LCLo (rat) = 4,000 ppm/4H

Explanatory Notes

Detection odor threshold from AIHA (mean = 0.080 ppm); The smell is detectable at 0.12 ppm and strong at 3-10 ppm. [ACGIH] Flash point = 10 def F;

Reference Link

ICSC: n-Butylamine

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: