Agent Name

Aldrin

CAS Number

309-00-2

Formula

C12-H8-Cl6

Major Category

Pesticides

Synonyms

1,2,3,4,10,10-Hexachloro-1,4,4a,5,8,8a-hexahydro-endo-1,4-exo-5,8-dimethanonaphthalene; HHDN; Octalene; [NIOSH]

Category

Organochlorine Pesticides

Description

Colorless to dark-brown crystalline solid with a mild chemical odor. [Note: Formerly used as an insecticide.] [NIOSH]

Sources/Uses

Used as an insecticide;

Comments

Not currently registered or used in the USA, Aldrin converts to dieldrin in the body and in the environment. High-dose animal studies show that organochlorine insecticides can cause liver injury. [LaDou, p. 593] "No evidence of hepatic injury in humans as the result of environmental contamination." [Zimmerman, p. 414] See ATSDR ToxProfiles.

Restricted

In 1974, EPA banned all uses except termite control. In 1987, EPA banned all uses. [ATSDR ToxFAQs]

Reference Link

NIOSH Occupational Health Guidelines for Chemical Hazards: Aldrin

Exposure Assessment
Skin Designation (ACGIH)

Yes

Bioaccumulates

Yes

TLV (ACGIH)

0.05 mg/m3, inhalable fraction and vapor

PEL (OSHA)

0.25 mg/m3

MAK

0.25 mg/m3, inhalable fraction

IDLH (NIOSH)

25 mg/m3

Vapor Pressure

6.5E-5 mm Hg

Reference Link

ATSDR - ToxFAQs - Aldrin/Dieldrin

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Other Poison

Organochlorine Pesticide

IARC Carcinogen

Not Classifiable

ACGIH Carcinogen

Confirmed Animal

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: