Agent Name

Dieldrin

CAS Number

60-57-1

Formula

C12-H8-Cl6-O

Major Category

Pesticides

Synonyms

HEOD; 1,2,3,4,10,10-Hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-1,4-endo,exo-5,8-dimethanonaphthalene; [NIOSH]

Category

Organochlorine Pesticides

Description

Colorless to light-tan crystals with a mild, chemical odor. [insecticide]; [NIOSH]

Sources/Uses

Dieldrin was used in the past to control insects, primarily in corn and citrus production. [ACGIH]

Comments

Dieldrin is very toxic by ingestion, inhalation, and skin absorption. For occupational exposures the greatest hazard is through skin absorption. TLV Basis: Liver damage; Reproductive effect; CNS impairment; [ACGIH] High-dose animal studies show that organochlorine insecticides are toxic to the liver. [LaDou, p. 553] A case of Coomb's positive anemia associated with exposure to Dieldrin was reported in 1978. [Rosenstock, p. 460 "No evidence of hepatic injury in humans as the result of environmental contamination." [Zimmerman, p. 414]

Restricted

In 1974, EPA banned all uses except termite control. In 1987, EPA banned al uses. [ATSDR ToxFAQs]

Exposure Assessment
Skin Designation (ACGIH)

Yes

Bioaccumulates

Yes

TLV (ACGIH)

0.1 mg/m3, inhalable fraction and vapor

PEL (OSHA)

0.25 mg/m3

MAK

0.25 mg/m3, inhalable fraction

IDLH (NIOSH)

50 mg/m3

Vapor Pressure

8.0E-7 mm Hg

Reference Link

ATSDR - ToxFAQs - Aldrin/Dieldrin

Adverse Effects
Anemia

Anemia, Hemolytic

Hepatotoxin

Hepatotoxin, Secondary

Reproductive Toxin

Yes

Other Poison

Organochlorine Pesticide

IARC Carcinogen

Not Classifiable

ACGIH Carcinogen

Confirmed Animal

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: