Agent Name

DDT

Alternative Name

Dichlorodiphenyltrichloroethane

CAS Number

50-29-3

Formula

C14-H9-Cl5

Major Category

Pesticides

Synonyms

Dichlorodiphenyltrichloroethane; 1,1'-(2,2,2-Trichloroethylidene)bis(4-chlorobenzene); 1,1,1-Trichloor-2,2-bis(4-chloor fenyl)-ethaan [Dutch]; 1,1,1-Trichlor-2,2-bis(4-chlor-phenyl)-aethan [German]; 1,1,1-Trichloro-2,2-bis(4,4'-dichlorodiphenyl)ethane; 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane; 1,1,1-Trichloro-2,2-bis(p-chlorophenyl)ethane; 1,1,1-Trichloro-2,2-di(4-chlorophenyl)-ethane; 1,1,1-Tricloro-2,2-bis(4-cloro-fenil)-etano [Italian]; 1,1,1-Tricloro-2,2-bis(4-cloro-fenyl)-etano [Italian]; 1,1-Bis-(p-chlorophenyl)-2,2,2-trichloroethane; 2,2-Bis(p-chlorophenyl)-1,1,1-trichloroethane; 4,4'-DDT; 4,4'-Dichlorodiphenyltrichloroethane; Aavero-extra; Agritan; Anofex; Arkotine; Azotox M 33; Benzochloryl; Bosan Supra; Bovidermol; Chlofenotan; Chlorophenothan; Chlorophenothane; Chlorophenothanum; Chlorophenothanum technicum; Chlorophenotoxum; Chlorphenothan; Chlorphenotoxum; Citox; Clofenotane; Clofenotane technique; Clofenotano [INN-Spanish]; Clofenotanum [INN-Latin]; D.D.T. technique; DDT 50 WP; Deoval; Detox; Detox (pesticide); Detoxan; Dibovin; Dicophane; Didigam; Didimac; Dodat; Dykol; Estonate; Ethane, 1,1,1-trichloro-2,2-bis(4-chlorophenyl)-; Ethane, 1,1,1-trichloro-2,2-bis(p-chlorophenyl)-; Genitox; Gesafid; Gesarol; Guesarol; Gyron; Hildit; Ivoran; Ixodex; Klorfenoton [Swedish Pharmacopoeia]; Kopsol; Mutoxan; Neocid; Neocid (VAN); Neocidol; Neocidol (solid); OMS 0016 [French]; OMS 16; PEB1; Parachlorocidum; Pentachlorin; Pentech; Penticidum; Rukseam; Santobane; Tafidex; Trichlorobis(4-chlorophenyl)ethane; Zerdane; alpha,alpha-Bis(p-chlorophenyl)-beta,beta,beta-trichloroethane; p'-Zeidane [France]; p,p'-DDT; p,p'-Dichlorodiphenyltrichloroethane; [ChemIDplus]

Category

Organochlorine Pesticides

Description

Colorless crystals or off-white powder with a slight, aromatic odor. [pesticide]; [NIOSH]

Sources/Uses

Formerly used as an insecticide and pesticide; [HSDB]

Comments

Still used in some parts of the world, DDT persists in the environment and in animal tissues. It has been especially harmful to predator species of birds. High-dose animal studies show that organochlorine insecticides are toxic to the liver. [LaDou, p. 553] Allergic contact dermatitis reported in farmworkers; [Kanerva, p. 1777] "Despite the billions of pounds of DDT that have been manufactured and used, hepatic injury acquired as the result of occupational or environmental exposure to it remains to be reported." [Zimmerman, p. 413]

Restricted

All agricultural uses cancelled in 1972 by EPA; [Sullivan, p. 660]

Reference Link

EXTOXNET - DDT

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

Bioaccumulates

Yes

MAK

1 mg/m3

Excerpts from Documentation for IDLHs

Human data: Exposure of volunteers to 423 mg/m3 for periods of 1 hour/day for 6 days has been reported to only cause eye irritation [Neal et al. 1994]. It has been reported that 500 mg/kg is the lethal oral dose [Windholz 1983]. [Note: An oral dose of 500 mg/kg is equivalent to a 70kg worker being exposed to about 23,000 mg/m3 for 30 minutes, assuming a breathing rate of 50 liters per minute and 100% absorption.]

Vapor Pressure

2.0E-7 mm Hg

Half Life

1-2 years to eliminate absorbed dose; [TDR, p. 440]

Reference Link

ATSDR - ToxFAQs - DDT, DDE, and DDD

Flammability (NFPA)

2: High ambient temperature required

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Other Poison

Organochlorine Pesticide

IARC Carcinogen

Possible Carcinogen

NTP Carcinogen

Anticipated Human Carcinogen

ACGIH Carcinogen

Confirmed Animal

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: