Agent Name | Methoxychlor |
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CAS Number | 72-43-5 |
Formula | C16-H15-Cl3-O2 |
Major Category | Pesticides |
Synonyms | 1,1'-(2,2,2-Trichloroethylidene)bis(4-methoxybenzene); 1,1,1-Trichlor-2,2-bis(4-methoxy-phenyl)-aethan [German]; 1,1,1-Trichloro-2,2-bis(4-methoxyphenyl)ethane; 1,1,1-Trichloro-2,2-bis(p-anisyl)ethane; 1,1,1-Trichloro-2,2-bis(p-methoxyphenyl)ethane; 1,1,1-Trichloro-2,2-di(4-methoxyphenyl)ethane; 1,1-Bis(p-methoxyphenyl)-2,2,2-trichloroethane; 2,2,2-Trichloro-1,1-bis(4-methoxyphenyl)ethane; 2,2-Bis(p-anisyl)-1,1,1-trichloroethane; 2,2-Bis(p-methoxyphenyl)-1,1,1-trichloroethane; 2,2-Di-(p-methoxyphenyl)-1,1,1-trichloroethane; 2,2-Di-p-anisyl-1,1,1-trichloroethane; 4,4-(2,2,2-Trichloroethylidene)dianisole; Chemform; DMDT; Dianisyl trichloroethane; Dianisyltrichlorethane; Dimethoxy-DDT; Ethane, 1,1,1-trichloro-2,2-bis(p-methoxyphenyl)-; Ethane, 2,2-bis(p-anisyl)-1,1,1-trichloro-; Higalmetox; Maralate; Marlate; Methoxcide; Methoxy-DDT; Methoxychlor; Methoxychlor 2 EC; Methoxychlor, technical; Methoxychlore [ISO-French]; Metoksychlor [Polish]; Metox; Mezox K; Moxie; OMS 466; p,p'-Dimethoxydiphenyltrichloroethane; p,p'-Dwumetoksydwufenylotrojchloroetan [Polish]; p,p'-Methoxychlor; [ChemIDplus] |
Category | Organochlorine Pesticides |
Description | Colorless to light-yellow crystals with a slight, fruity odor. [insecticide]; [NIOSH] |
Sources/Uses | Used to kill insects on fruits, vegetables, and forest crops; used to kill parasites on cattle; [EXTOXNET] |
Comments | Methoxychlor is classified as "practically nontoxic" with an LD50 of 5-6 gm/kg in rats. It does not accumulate in tissues of mammals, but is highly toxic to fish. It persists in the soil with a half-life estimate of 120 days. [EXTOXNET] High-dose animal studies show that organochlorine insecticides can cause liver injury. [LaDou, p. 593] "No evidence of hepatic injury in humans as the result of environmental contamination." [Zimmerman, p. 414] |
Reference Link | |
Exposure Assessment | |
Skin Designation (ACGIH) | Insufficient data |
Bioaccumulates | Yes |
TLV (ACGIH) | 10 mg/m3 |
PEL (OSHA) | 15 mg/m3, total dust |
MAK | 1 mg/m3, inhalable fraction |
IDLH (NIOSH) | 5000 mg/m3 |
Vapor Pressure | 2.58E-6 mm Hg |
Half Life | Animal studies: most of dose eliminated within a few days;; [TDR, p. 837] |
Reference Link | |
Adverse Effects | |
Hepatotoxin | Hepatotoxin, Secondary |
Other Poison | Organochlorine Pesticide |
IARC Carcinogen | Not Classifiable |
ACGIH Carcinogen | Not Classifiable |
Links to Other NLM Databases | |
Health Studies | Human Health Effects from Hazardous Substances Data Bank: |
Toxicity Information | |
Chemical Information | |
Related Information in HazMap | |
Diseases | Occupational diseases associated with exposure to this agent: |
Processes | Industrial Processes with risk of exposure: |