| Agent Name | Methoxychlor |
|---|---|
| CAS Number | 72-43-5 |
| Formula | C16-H15-Cl3-O2 |
| Major Category | Pesticides |
| Synonyms | 1,1'-(2,2,2-Trichloroethylidene)bis(4-methoxybenzene); 1,1,1-Trichlor-2,2-bis(4-methoxy-phenyl)-aethan [German]; 1,1,1-Trichloro-2,2-bis(4-methoxyphenyl)ethane; 1,1,1-Trichloro-2,2-bis(p-anisyl)ethane; 1,1,1-Trichloro-2,2-bis(p-methoxyphenyl)ethane; 1,1,1-Trichloro-2,2-di(4-methoxyphenyl)ethane; 1,1-Bis(p-methoxyphenyl)-2,2,2-trichloroethane; 2,2,2-Trichloro-1,1-bis(4-methoxyphenyl)ethane; 2,2-Bis(p-anisyl)-1,1,1-trichloroethane; 2,2-Bis(p-methoxyphenyl)-1,1,1-trichloroethane; 2,2-Di-(p-methoxyphenyl)-1,1,1-trichloroethane; 2,2-Di-p-anisyl-1,1,1-trichloroethane; 4,4-(2,2,2-Trichloroethylidene)dianisole; Chemform; DMDT; Dianisyl trichloroethane; Dianisyltrichlorethane; Dimethoxy-DDT; Ethane, 1,1,1-trichloro-2,2-bis(p-methoxyphenyl)-; Ethane, 2,2-bis(p-anisyl)-1,1,1-trichloro-; Higalmetox; Maralate; Marlate; Methoxcide; Methoxy-DDT; Methoxychlor; Methoxychlor 2 EC; Methoxychlor, technical; Methoxychlore [ISO-French]; Metoksychlor [Polish]; Metox; Mezox K; Moxie; OMS 466; p,p'-Dimethoxydiphenyltrichloroethane; p,p'-Dwumetoksydwufenylotrojchloroetan [Polish]; p,p'-Methoxychlor; [ChemIDplus] |
| Category | Organochlorine Pesticides |
| Description | Colorless to light-yellow crystals with a slight, fruity odor. [insecticide]; [NIOSH] |
| Sources/Uses | Used to kill insects on fruits, vegetables, and forest crops; used to kill parasites on cattle; [EXTOXNET] |
| Comments | Methoxychlor is classified as "practically nontoxic" with an LD50 of 5-6 gm/kg in rats. It does not accumulate in tissues of mammals, but is highly toxic to fish. It persists in the soil with a half-life estimate of 120 days. [EXTOXNET] High-dose animal studies show that organochlorine insecticides can cause liver injury. [LaDou, p. 593] "No evidence of hepatic injury in humans as the result of environmental contamination." [Zimmerman, p. 414] |
| Reference Link | |
| Exposure Assessment | |
| Skin Designation (ACGIH) | Insufficient data |
| Bioaccumulates | Yes |
| TLV (ACGIH) | 10 mg/m3 |
| PEL (OSHA) | 15 mg/m3, total dust |
| MAK | 1 mg/m3, inhalable fraction |
| IDLH (NIOSH) | 5000 mg/m3 |
| Vapor Pressure | 2.58E-6 mm Hg |
| Half Life | Animal studies: most of dose eliminated within a few days;; [TDR, p. 837] |
| Reference Link | |
| Adverse Effects | |
| Hepatotoxin | Hepatotoxin, Secondary |
| Other Poison | Organochlorine Pesticide |
| IARC Carcinogen | Not Classifiable |
| ACGIH Carcinogen | Not Classifiable |
| Links to Other NLM Databases | |
| Health Studies | Human Health Effects from Hazardous Substances Data Bank: |
| Toxicity Information | |
| Chemical Information | |
| Related Information in HazMap | |
| Diseases | Occupational diseases associated with exposure to this agent: |
| Processes | Industrial Processes with risk of exposure: |
Agent Name
Methoxychlor
CAS Number
72-43-5
Formula
C16-H15-Cl3-O2
Major Category
Pesticides
Synonyms
1,1'-(2,2,2-Trichloroethylidene)bis(4-methoxybenzene); 1,1,1-Trichlor-2,2-bis(4-methoxy-phenyl)-aethan [German]; 1,1,1-Trichloro-2,2-bis(4-methoxyphenyl)ethane; 1,1,1-Trichloro-2,2-bis(p-anisyl)ethane; 1,1,1-Trichloro-2,2-bis(p-methoxyphenyl)ethane; 1,1,1-Trichloro-2,2-di(4-methoxyphenyl)ethane; 1,1-Bis(p-methoxyphenyl)-2,2,2-trichloroethane; 2,2,2-Trichloro-1,1-bis(4-methoxyphenyl)ethane; 2,2-Bis(p-anisyl)-1,1,1-trichloroethane; 2,2-Bis(p-methoxyphenyl)-1,1,1-trichloroethane; 2,2-Di-(p-methoxyphenyl)-1,1,1-trichloroethane; 2,2-Di-p-anisyl-1,1,1-trichloroethane; 4,4-(2,2,2-Trichloroethylidene)dianisole; Chemform; DMDT; Dianisyl trichloroethane; Dianisyltrichlorethane; Dimethoxy-DDT; Ethane, 1,1,1-trichloro-2,2-bis(p-methoxyphenyl)-; Ethane, 2,2-bis(p-anisyl)-1,1,1-trichloro-; Higalmetox; Maralate; Marlate; Methoxcide; Methoxy-DDT; Methoxychlor; Methoxychlor 2 EC; Methoxychlor, technical; Methoxychlore [ISO-French]; Metoksychlor [Polish]; Metox; Mezox K; Moxie; OMS 466; p,p'-Dimethoxydiphenyltrichloroethane; p,p'-Dwumetoksydwufenylotrojchloroetan [Polish]; p,p'-Methoxychlor; [ChemIDplus]
Category
Organochlorine Pesticides
Description
Colorless to light-yellow crystals with a slight, fruity odor. [insecticide]; [NIOSH]
Sources/Uses
Used to kill insects on fruits, vegetables, and forest crops; used to kill parasites on cattle; [EXTOXNET]
Comments
Methoxychlor is classified as "practically nontoxic" with an LD50 of 5-6 gm/kg in rats. It does not accumulate in tissues of mammals, but is highly toxic to fish. It persists in the soil with a half-life estimate of 120 days. [EXTOXNET] High-dose animal studies show that organochlorine insecticides can cause liver injury. [LaDou, p. 593] "No evidence of hepatic injury in humans as the result of environmental contamination." [Zimmerman, p. 414]
Reference Link
Exposure Assessment
Skin Designation (ACGIH)
Insufficient data
Bioaccumulates
Yes
TLV (ACGIH)
10 mg/m3
PEL (OSHA)
15 mg/m3, total dust
MAK
1 mg/m3, inhalable fraction
IDLH (NIOSH)
5000 mg/m3
Vapor Pressure
2.58E-6 mm Hg
Half Life
Animal studies: most of dose eliminated within a few days;; [TDR, p. 837]
Reference Link
Adverse Effects
Hepatotoxin
Hepatotoxin, Secondary
Other Poison
Organochlorine Pesticide
IARC Carcinogen
Not Classifiable
ACGIH Carcinogen
Not Classifiable
Links to Other NLM Databases
Toxicity Information
Chemical Information
Related Information in HazMap
Diseases
Occupational diseases associated with exposure to this agent: