Agent Name

Allyl alcohol

CAS Number

107-18-6

Formula

C3-H6-O

Major Category

Toxic Gases & Vapors

Synonyms

2-Propen-1-ol; 2-Propenol; 2-Propenyl alcohol; 3-Hydroxypropene; Alcool allilco [Italian]; Alcool allylique [French]; Allilowy alkohol [Polish]; Allyl alcohol; Allylalkohol [German]; Allylic alcohol; Propen-1-ol-3; Propenyl alcohol; Shell unkrautted A; Vinyl carbinol; Vinylcarbinol; Weed drench; [ChemIDplus] UN1098

Category

Other Toxic Gases & Vapors

Description

Colorless liquid with a pungent, mustard-like odor; [NIOSH]

Sources/Uses

Used to produce resins, plasticizers, pharmaceuticals, and other organic chemicals; has been used in chemical warfare; [ACGIH] Used exclusively as an intermediate in chemical manufacture; [Reference #1]

Comments

Liquid causes first degree burns on short exposure; [CHRIS] Pulmonary congestion and hepatic injury in acute animal studies; [ACGIH] A lachrymator; [CHEMINFO] A skin, eye, and respiratory tract irritant; Causes lachrymation; May have effects on the muscles (local spasm and aching); May cause liver and kidney injury; [ICSC] May cause eye and nasal mucosa irritation; [Reference #1] A strong reducing agent that may polymerize; A severe skin, eye, nose, and throat irritant (may cause burns on contact); Inhalation may cause pulmonary edema; [CAMEO] A skin, respiratory tract, and strong eye irritant; A photosensitizer and lachrymator; Toxic ingestion; Highly toxic by inhalation and skin absorption; Targets the liver, lung, and kidney; [Aldrich MSDS]

Reference Link

OECD SIDS: 2-Propen-1-ol - 2005

Exposure Assessment
Skin Designation (ACGIH)

Yes

TIH

Yes

TLV (ACGIH)

0.5 ppm

PEL (OSHA)

2 ppm

IDLH (NIOSH)

20 ppm

Excerpts from Documentation for IDLHs

Human data: Severe eye irritation is reported to result from exposure at 25 ppm [Dunlap et al. 1958].

Vapor Pressure

26.1 mm Hg

Odor Threshold Low

1.4 ppm

Odor Threshold High

2.1 ppm

RD50

4 ppm

Lethal Concentration

LC50 (rat) = 76 ppm/8hr

Explanatory Notes

Detection odor threshold from AIHA (mean = 1.7 ppm); Flash point = 22 deg C;

Reference Link

ICSC: Allyl alcohol

Adverse Effects
Lacrimator

Yes

Toxic Pneumonitis

Yes

Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: