Agent Name

Dichlorvos

Alternative Name

DDVP

CAS Number

62-73-7

Formula

C4-H7-Cl2-O4-P

Major Category

Pesticides

Synonyms

DDVP; 2,2-Dichlorovinyl dimethyl phosphate; Apavap; Benfos; Cekusan; Cypona; Derriban; Derribante; Devikol; Didivane; Duo-Kill; Duravos; Elastrel; Fly-Bate; Fly-Die; Fly-Fighter; Herkol; Marvex; No-Pest; Prentox; Vaponite; Vapona; Verdican; Verdipor; Verdisol; DDVP

Category

Organophosphate Insecticides

Description

Colorless to amber liquid with a mild, chemical odor. [NIOSH]

Sources/Uses

Used for insect control in food storage areas, greenhouses, and barns; it is not commonly used on field crops; [ATSDR ToxFAQs] Used to kill internal and external parasites of fish, other animals, and humans; [ACGIH]

Comments

A small number of the organophosphates (Ops) can Induce Delayed Neuropathy (OPIDN). OPIDN usually occurs after ingestion and is usually nonoccupational. [Levy, p. 431] Allergic contact dermatitis reported in flower growers and horticulturists; [Kanerva, p. 1780] Because of its relatively high vapor pressure, confined space exposure can cause significant poisoning. [AHLS, p. 237] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]

Restricted

Classified as $highly toxic,$ dichlorvos may be used only by certified applicators. [EXTOXNET]

Reference Link

EXTOXNET - Dichlorvos

Exposure Assessment
BEI

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Skin Designation (ACGIH)

Yes

TLV (ACGIH)

0.1 mg/m3, inhalable fraction and vapor

PEL (OSHA)

1 mg/m3

MAK

1 mg/m3

IDLH (NIOSH)

100 mg/m3

Vapor Pressure

0.01 mm Hg

Reference Link

ATSDR - ToxFAQs - Dichlorvos

Adverse Effects
Skin Sensitizer

Yes

Neurotoxin

Motor Neuropathy

Other Poison

Organophosphate

IARC Carcinogen

Possible Carcinogen

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: