Agent Name

Lead(IV) acetate

CAS Number

546-67-8

Formula

C2-H4-O2.1/4Pb

Major Category

Metals

Synonyms

Acetic acid, lead(4+) salt; Lead acetate (Pb(O2C2H3)4); Lead acetate (Pb(OAc)4); Lead acetate, tetra-; Lead tetraacetate; Lead tetracetate; Plumbic acetate; [ChemIDplus]

Category

Organic Acids, Metal Salts

Description

Colorless to pink solid from glacial acetic acid; [Merck Index # 5423]

Sources/Uses

Used in organic syntheses; [HSDB]

Comments

Contact causes severe irritation of eyes and can burn skin; [CAMEO] Toxic substance that can be absorbed through skin; [Hawley] See "Lead" and linked occupational diseases.

Exposure Assessment
BEI

Lead in blood = 200 ug/L (20 ug/100 ml); sampling time not critical; [ACGIH]

TLV (ACGIH)

0.05 mg/m3, as Pb

PEL (OSHA)

0.05 mg/m3, as Pb

Explanatory Notes

mp = 175 deg C; [[Ullmann]

Adverse Effects
Anemia

Anemia, Hemolytic

Neurotoxin

Motor Neuropathy

Nephrotoxin

Yes

Reproductive Toxin

Yes

IARC Carcinogen

Probable Carcinogen

NTP Carcinogen

Anticipated Human Carcinogen

ACGIH Carcinogen

Confirmed Animal

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: