Agent Name

TEPP

Alternative Name

Tetraethylpyrophosphate

CAS Number

107-49-3

Formula

C8-H20-O7-P2

Major Category

Pesticides

Synonyms

Tetraethylpyrophosphate; Bis-O,O-diethylphosphoric anhydride; Bladan; Bladan (VAN); Diphosphoric acid tetraethyl ester; EA 1285; Ethyl pyrophosphate; Ethyl pyrophosphate (Et4P2O7); Ethyl pyrophosphate, tetra-; Fosvex; Grisol; HEPT; Hepthexamite; Hexamite; Killax; Killex; Kilmite 40; Lethalaire G-52; Lirohex; Mortopal; Nifos; Nifos T; Nifost; O,O,O,O-Tetraaethyl-diphosphat, bis(O,O-diaethylphosphorsaeure-anhydrid) [German]; O,O,O,O-Tetraethyl-difosfaat [Dutch]; O,O,O,O-Tetraetil-pirofosfato [Italian]; Pyrophosphate de tetraethyle [French]; TEPP; Tetraaethylpyrophosphorsaeureester [German]; Tetraethyl diphosphate; Tetraethyl pyrofosfaat [Belgian]; Tetraethyl pyrofosfaat [Dutch]; Tetraethyl pyrophosphate; Tetraethyldifosfat [Czech]; Tetraethylpyrofosfat [Czech]; Tetraethylpyrophosphate; Tetraethylpyrophosphorsaeureester [German]; Tetrastigmine; Tetron; Tetron-100; Vapotone; [ChemIDplus]

Category

Organophosphate Insecticides

Description

Colorless to amber liquid with a faint, fruity odor. [insecticide] [Note: A solid below 32 degrees F.]; [NIOSH]

Sources/Uses

Commercially available as dust, concentrate, or solution in methyl chloride to kill aphids, spiders, mites, mealy bugs, leafhoppers, and thirps; [ACGIH] Used on vegetable and fruit crops, it is one of the first organophosphate insecticide developed and has been largely replaced by newer products. [HSDB]

Comments

Many deaths have been reported, most after suicidal ingestion. Several cases of severe poisoning and death have been reported after spills in which workers clothing was contaminated. [ACGIH]

Exposure Assessment
BEI

Cholinesterase activity in red cells = 70% of individual's baseline, sample time discretionary; [ACGIH]

Skin Designation (ACGIH)

Yes

TLV (ACGIH)

0.01 mg/m3, inhalable fraction and vapor

PEL (OSHA)

0.05 mg/m3

MAK

0.06 mg/m3

IDLH (NIOSH)

5 mg/m3

Vapor Pressure

0.00015 mm Hg

Lethal Concentration

LC50 (rat) = 7 mg/m3/4H; [ACGIH]

Adverse Effects
Other Poison

Organophosphate

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: