| Agent Name | Fenamiphos |
|---|---|
| CAS Number | 22224-92-6 |
| Formula | C13-H22-N-O3-P-S |
| Major Category | Pesticides |
| Synonyms | 1-(Methylethyl)-ethyl 3-methyl-4-(methylthio)phenyl phosphoramidate; BAY 68138; BAY sra 3886; Ethyl 3-methyl-4-(methylthio)phenyl (1-methylethyl)phosphoramidate; Ethyl 3-methyl-4-(methylthio)phenyl isopropylphosphoramidate; Ethyl 4-(methylthio)-m-tolyl isopropylphosphoramidate; Fenamiphos; Isopropylamino-O-ethyl-(4-methylmercapto-3-methylphenyl)phosphate; Methaphenamiphos; Nemacur; Nemacur P; O-Aethyl-O-(3-methyl-4-methylthiophenyl)-isopropylamido-phosphorsaeureester [German]; Phenamiphos; Phenamiphos [ISO-French]; Phosphoramidic acid, isopropyl-, ethyl 4-(methylthio)-m-tolyl ester; SRA 3886; [ChemIDplus] |
| Category | Organophosphate Insecticides |
| Description | Off-white to tan, waxy solid. [insecticide] [Note: Found commercially as a granular ingredient (5-15%) or in an emulsifiable concentrate (400 g/l).]; [NIOSH] |
| Sources/Uses | Fenamiphos is a systemic, organophosphate nematicide used on tobacco, turf, bananas, pineapples, citrus crops, vegetables, and grains. [EXTOXNET] |
| Comments | Classified as "highly toxic" and may be used only by a certified applicator; [EXTOXNET] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs] |
| Reference Link | |
| Exposure Assessment | |
| BEI | Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs] |
| Skin Designation (ACGIH) | Yes |
| TLV (ACGIH) | 0.05 mg/m3, inhalable fraction and vapor |
| Vapor Pressure | 5.0E-5 mm Hg |
| Lethal Concentration | LC50 (rat) = 91 mg/m3/4h |
| Reference Link | |
| Adverse Effects | |
| Other Poison | Organophosphate |
| ACGIH Carcinogen | Not Classifiable |
| Links to Other NLM Databases | |
| Health Studies | Human Health Effects from Hazardous Substances Data Bank: |
| Toxicity Information | |
| Chemical Information | |
| Biomedical References | |
| Related Information in HazMap | |
| Diseases | Occupational diseases associated with exposure to this agent: |
| Processes | Industrial Processes with risk of exposure: |
Agent Name
Fenamiphos
CAS Number
22224-92-6
Formula
C13-H22-N-O3-P-S
Major Category
Pesticides
Synonyms
1-(Methylethyl)-ethyl 3-methyl-4-(methylthio)phenyl phosphoramidate; BAY 68138; BAY sra 3886; Ethyl 3-methyl-4-(methylthio)phenyl (1-methylethyl)phosphoramidate; Ethyl 3-methyl-4-(methylthio)phenyl isopropylphosphoramidate; Ethyl 4-(methylthio)-m-tolyl isopropylphosphoramidate; Fenamiphos; Isopropylamino-O-ethyl-(4-methylmercapto-3-methylphenyl)phosphate; Methaphenamiphos; Nemacur; Nemacur P; O-Aethyl-O-(3-methyl-4-methylthiophenyl)-isopropylamido-phosphorsaeureester [German]; Phenamiphos; Phenamiphos [ISO-French]; Phosphoramidic acid, isopropyl-, ethyl 4-(methylthio)-m-tolyl ester; SRA 3886; [ChemIDplus]
Category
Organophosphate Insecticides
Description
Off-white to tan, waxy solid. [insecticide] [Note: Found commercially as a granular ingredient (5-15%) or in an emulsifiable concentrate (400 g/l).]; [NIOSH]
Sources/Uses
Fenamiphos is a systemic, organophosphate nematicide used on tobacco, turf, bananas, pineapples, citrus crops, vegetables, and grains. [EXTOXNET]
Comments
Classified as "highly toxic" and may be used only by a certified applicator; [EXTOXNET] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]
Reference Link
Exposure Assessment
BEI
Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]
Skin Designation (ACGIH)
Yes
TLV (ACGIH)
0.05 mg/m3, inhalable fraction and vapor
Vapor Pressure
5.0E-5 mm Hg
Lethal Concentration
LC50 (rat) = 91 mg/m3/4h
Reference Link
Adverse Effects
Other Poison
Organophosphate
ACGIH Carcinogen
Not Classifiable
Links to Other NLM Databases
Toxicity Information
Chemical Information
Biomedical References
Related Information in HazMap
Diseases
Occupational diseases associated with exposure to this agent: