Agent Name

3-Chloro-2-methyl-1-propene

Alternative Name

Methallyl chloride

CAS Number

563-47-3

Formula

C4-H7-Cl

Major Category

Other Classes

Synonyms

Methallyl chloride; 3-Chloro-2-methylprop-1-ene; 3-Chloro-2-methylpropene; 1-Chloro-2-methyl-2-propene; 2-Methallyl chloride; 2-Methyl-2-propenyl chloride; 2-Methyl-allylchlorid [German]; 2-Methylallyl chloride; 3-Chlor-2-methyl-prop-1-en [German]; 3-Chloro-2-Methylpropene; 3-Chloro-2-methylpropene (IUPAC); 3-Chloroisobutylene; 3-Cloro-2-metil-prop-1-ene [Italian]; Chlorue de methallyle [French]; Chlorure de methallyle [French]; Cloruro di metallile [Italian]; Isobutenyl chloride; MAC; Methallyl chloride; Propene, 3-chloro-2-methyl-; beta-Methylallyl chloride; gamma-Chloroisobutylene; [ChemIDplus] UN2554

Category

Halogenated Aliphatics, Unsaturated

Description

Colorless to yellow liquid, with pungent odor; [ICSC] Odor: stench; [MSDSonline]

Sources/Uses

Used to make insecticides, plastics, pharmaceuticals, and other chemicals; Also used as a fumigant for grains, tobacco, and soil; [Hawley]

Comments

A skin, eye, and respiratory tract irritant; Tear drawing; Inhalation of high concentrations may cause CNS effects; May cause skin sensitization; [ICSC] Dangerous fire risk; Explosive limits in air are 3.2 - 8.1%; [Hawley] Harmful by inhalation and ingestion; Causes burns; Lachrymatory effect; May cause skin sensitization; [MSDSonline] See "Carcinogenicity of some industrial chemicals," Volume 115. [IARC, News Release, 23 February 2016] Methylallyl chloride (UN2554) has warning of explosive polymerization; [ERG 2016]

Exposure Assessment
Vapor Pressure

102 mm Hg

Lethal Concentration

LC50 (rat) = 34,000 mg/m3/30 min

Explosive Polymerization

Yes

Explanatory Notes

Flash point = -12 deg C; [HSDB]

Adverse Effects
Skin Sensitizer

Yes

Lacrimator

Yes

Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

IARC Carcinogen

Not Classifiable

NTP Carcinogen

Anticipated Human Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: