Agent Name

Isobutyraldehyde

CAS Number

78-84-2

Formula

C4-H8-O

Major Category

Other Classes

Synonyms

2-Methyl-1-propanal; 2-Methylpropanal; 2-Methylpropionaldehyde; Isobutaldehyde; Isobutanal; Isobutylaldehyde; Isobutyral; Isobutyraldehyd [Czech]; Isobutyraldehyde (natural); Isobutyric aldehyde; Isobutyryl aldehyde; Isopropyl aldehyde; Isopropyl formaldehyde; Isopropylaldehyde; Isopropylformaldehyde; Methyl propanal; Methylpropanal; Propanal, 2-methyl-; Propionaldehyde, 2-methyl-; Valine aldehyde; alpha-Methylpropionaldehyde; [ChemIDplus] UN2045

Category

Aldehydes

Description

Clear liquid with pungent odor; [Hawley] Colorless liquid; [MSDSonline]

Sources/Uses

Used in organic synthesis (pantothenic acid, valine, leucine, cellulose esters, perfumes, flavors, plasticizers, resins, and gasoline additives); [Merck Index] Used as a chemical intermediate; [Hawley] An FDA-approved flavoring agent and it occurs naturally in foods; [AIHA]

Comments

A corrosive substance that can cause pulmonary edema; Can cause skin burns; Can cause severe burns to eyes; [ICSC] Inhalation of high concentrations can cause CNS depression; [HSDB] An irritant; [MSDSonline] No irritation in 15 volunteers exposed to 210 ppm, but two became nauseated; [AIHA]

Exposure Assessment
WEEL

25 ppm

Vapor Pressure

173 mm Hg

Odor Threshold Low

0.14 ppm

Odor Threshold High

0.3 ppm

Lethal Concentration

LCLo (rat) = 8,000 ppm/4h

Explanatory Notes

Flash point = -25 deg C; [ICSC] Odor threshold (recognition) from CHEMINFO;

Adverse Effects
Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.