Agent Name

Disulfoton

CAS Number

298-04-4

Formula

C8-H19-O2-P-S3

Major Category

Pesticides

Synonyms

BAY 19639; Bayer 19639; Di-Syston G; Di-syston; Disulfoton; Dithiodemeton; Dithiophosphate de O,O-diethyle et de S-(2-ethylthio-ethyle) [French]; Dithiosystox; Dution; Ekatin TD; Ekatine; Ethyl thiometon; Ethylthiometon B; Frumin; Frumin AL; Frumin G; Glebofos; Insyst-D; M-74; M-74 (Pesticide); O,O-Diaethyl-S-(2-aethylthio-aethyl)-dithiophosphat [German]; O,O-Diaethyl-S-(3-thia-pentyl)-dithiophosphat [German]; O,O-Diethyl 2-ethylthioethyl phosphorodithioate; O,O-Diethyl S-(2-(ethylthio)ethyl) dithiophosphate; O,O-Diethyl S-(2-(ethylthio)ethyl)phosphorodithioate; O,O-Diethyl S-(2-eththioethyl) phosphorodithioate; O,O-Diethyl S-(2-eththioethyl) thiothionophosphate; O,O-Diethyl S-(2-ethylmercaptoethyl) dithiophosphate; O,O-Diethyl S-2-(ethylthio)ethyl phosphorodithioate; O,O-Diethyl-S-(2-ethylthio-ethyl)-dithiofosfaat [Dutch]; O,O-Diethyl-S-ethylmercapto-ethyl dithiophosphate; O,O-Dietil-S-(2-etiltio-etil)-ditiofosfato [Italian]; S 276; S-2-(Ethylthio)ethyl O,O-diethyl ester of phosphorodithioic acid; Solvigran; Solvirex; Thiodemeton; Vuagt 1-4; Vuagt 1964; [ChemIDplus]

Category

Organophosphate Insecticides

Description

Oily, colorless to yellow liquid with a characteristic, sulfur odor. [insecticide] [Note: Technical product is a brown liquid.]; [NIOSH]

Sources/Uses

Used on cotton, tobacco, sugar beets, corn, peanuts, wheat, ornamentals, cereal grains, and potatoes; [EXTOXNET]

Comments

Disulfoton is classified as "highly toxic." Formulations of greater than 2% disulfoton may be used only by certified applicators. [EXTOXNET] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]

Reference Link

EXTOXNET PIP - DISULFOTON

Exposure Assessment
BEI

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Skin Designation (ACGIH)

Yes

TLV (ACGIH)

0.05 mg/m3, inhalable fraction and vapor

Vapor Pressure

0.0002 mm Hg

Lethal Concentration

LC50 (rat) = 200 mg/m3

Reference Link

ATSDR - ToxFAQs - Disulfoton

Adverse Effects
Other Poison

Organophosphate

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: