Agent Name

2-Chloro-1,1,1-trifluoroethane

CAS Number

75-88-7

Formula

C2-H2-Cl-F3

Major Category

Solvents

Synonyms

1,1,1-Trifluoro-2-chloroethane; 1,1,1-Trifluoroethyl chloride; 1-Chloro-2,2,2-trifluoroethane; 2,2,2-Trifluorochloroethane; CFC 133a; FC 133a; Forane 133a; Freon 133a; Genetron 133a; HCFC 133a; R 133a; Chloro-1,1,1-trifluoroethane; Ethane, 2-chloro-1,1,1-trifluoro-; Chlorotrifluoroethane; [ChemIDplus] UN1983

Category

Chlorofluorocarbons

Description

A colorless gas; Shipped as a liquid under its own vapor pressure; [CAMEO]

Sources/Uses

Used as a blowing agent, refrigerant, and chemical intermediate; [HSDB]

Comments

In confined space spill, may displace air and act as simple asphyxiant; Evaporating liquid can cause frostbite; "Exposure at high level may result in unconsciousness." [ICSC] Effects in high-dose animal studies include general anesthesia; [MSDSonline]

Exposure Assessment
Lethal Concentration

LC50 (mice) = 150,000 ppm/1h

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Other Poison

Simple Asphyxiant

IARC Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: