Agent Name

1,1,2,3-Tetrachloropropene

CAS Number

10436-39-2

Formula

C3-H2-Cl4

Major Category

Other Classes

Synonyms

1-Propene, 1,1,2,3-tetrachloro-; Propene, 1,1,2,3-tetrachloro-; [ChemIDplus] TCPP; [IUCLID] TCP; Tetrachloropropene; [ToxPlanet: EPA - TSCATS]

Category

Halogenated Aliphatics, Unsaturated

Description

Liquid; [IUCLID]

Comments

No significant adverse effects observed in 13 week inhalation study with rats; No significant adverse effects observed in reproductive inhalation study with rats; Necrotic lesions of the liver were observed in rats at gavage doses of 300 mg/kg for one month; Effects in dermal LD50 study with rabbits include skin necrosis followed by eschar formation and exfoliation; Severely irritating to skin (superficial necrosis) and moderately irritating to eyes (with conjunctival redness, chemosis, and discharge) of rabbits; All eye irritation reversed within 7 days; [HSDB]

Exposure Assessment
Vapor Pressure

2.67 mm Hg

Lethal Concentration

LC50 (rat) = 1,500 mg/m3

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.