Agent Name

Ronnel

CAS Number

299-84-3

Formula

C8-H8-Cl3-O3-P-S

Major Category

Pesticides

Synonyms

Blitex; Dermafos; Dermafosu [Polish]; Dermaphos; Dimethyl (2,4,5-trichlorophenyl) phosphorothionate; Dimethyl trichlorophenyl thiophosphate; Dow ET 14; Dow ET 57; ET 14; ET 57; Ectoral; Etrolene; Fenchloorfos [Dutch]; Fenchlorfos; Fenchlorfosu [Polish]; Fenchlorphos; Fenchlorphos [ISO]; Fenclofos; Fenclofosum [INN-Latin]; Gesektin K; Korlan; Korlane; Moorman's Medicated Rid-Ezy; Nanchor; Nanker; Nankor; O,O-Dimethyl O-(2,4,5-trichlorophenyl) phosphorothioate; O,O-Dimethyl O-(2,4,5-trichlorophenyl)thiophosphate; O,O-Dimethyl-O-(2,4,5-trichlorphenyl)-thionophosphat [German]; O-(2,4,5-Trichloor-fenyl)-O,O-dimethyl-monothiofosfaat [Dutch]; O-(2,4,5-Trichlor-phenyl)-O,O-dimethyl-monothiophosphat [German]; O-(2,4,5-Tricloro-fenil)-O,O-dimetil-monotiofosfato [Italian]; OMS 123; Phenchlorfos; Phenol, 2,4,5-trichloro-, O-ester with O,O-dimethyl phosphorothioate; Phenol, 2,4,5-trichloro-, O-ester with O,O-dimethylphosphorothioate; Phosphorothioic acid, O,O-dimethyl O-(2,4,5-trichlorophenyl) ester (8CI)(9CI); Remelt; Ronnel [ANSI]; Rovan; Smear; Thiophosphate de O,O-dimethyle et de O-(2,4,5-trichlorophenyle) [French]; Trichlormetaphos; Trichlorometafos; Trolene; Trolene 20L; Viozene; [ChemIDplus]

Category

Organophosphate Insecticides

Description

White to light-tan, crystalline solid. [insecticide] [Note: A liquid above 106 degrees F.]; [NIOSH]

Sources/Uses

Used as an oral or topical medication to kill insects infesting cattle; [ACGIH]

Comments

Ronnel is corrosive to the skin. [AHLS, p. 105] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]

Exposure Assessment
BEI

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Skin Designation (ACGIH)

No

TLV (ACGIH)

5 mg/m3, inhalable fraction and vapor

PEL (OSHA)

15 mg/m3

IDLH (NIOSH)

300 mg/m3

Excerpts from Documentation for IDLHs

Basis for revised IDLH: No inhalation toxicity data are available on which to base an IDLH for ronnel. Therefore, the revised IDLH for ronnel is 300 mg/m3 based on acute oral toxicity in animals [AAPCO 1966; Klimmer 1971]. This may be a conservative value due to the lack of relevant acute toxicity data for workers.

Vapor Pressure

0.0008 mm Hg

Adverse Effects
Other Poison

Organophosphate

Dermatotoxin

Skin Burns

ACGIH Carcinogen

Not Classifiable

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Diseases

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