Agent Name

Diepoxybutane

CAS Number

1464-53-5

Formula

C4-H6-O2

Major Category

Plastics & Rubber

Synonyms

1,1'-Bi(ethylene oxide); 1,2:3,4-Butadiene diepoxide; 1,2:3,4-Diepoxybutane; 1,3-Butadiene diepoxide; 2,2'-Bioxirane; Bioxiran; Bioxirane; Butadiendioxyd [German]; Butadiene diepoxide; Butadiene dioxide; Butane diepoxide; CB 1181; Dioxybutadiene; M 8838; R 181; Threitol, 1,2:3,4-dianhydro-; [ChemIDplus] UN2929

Category

Epoxides

Description

Colorless liquid; [CAMEO] Very faintly yellow clear liquid; [MSDSonline]

Sources/Uses

Used for curing polymers, cross-linking textile fibers, and producing erythritol and pharmaceuticals; [HSDB] Used to prevent spoilage; [CAMEO]

Comments

A strong skin and eye irritant; [HSDB] May cause burns; Toxic by ingestion and skin absorption; Very toxic by inhalation; [eChemPortal: ESIS] "Germ cell mutagens that have shown to increase the mutant frequency in the progeny of exposed mammals." [MAK] A severe irritant; May cause burns; May cause burns to the respiratory tract after inhalation; [MSDSonline]

Exposure Assessment
Vapor Pressure

39 mm Hg

Lethal Concentration

LC50 (rat) = 90 ppm/4h

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Toxic liquid, flammable, n.o.s. (Inhalation Hazard Zone B)."

Adverse Effects
Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

IARC Carcinogen

Known Carcinogen

NTP Carcinogen

Anticipated Human Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: