Agent Name

1,2,3,6-Tetrahydrophthalimide

CAS Number

85-40-5

Formula

C8-H9-N-O2

Major Category

Pesticides

Synonyms

1H-Isoindole-1,3(2H)-dione, 3a,4,7,7a-tetrahydro-; 4-Cyclohexene-1,2-dicarboximide; Isoindole-1,3-dione, 3a,4,7,7a-tetrahydro-; Tetrahydrophthalic acid imide; Tetrahydrophthalimide; Tetrahydrophthalimide (VAN); delta(4)-Tetrahydrophthalimide; delta(sup 4)-Tetrahydrophthalimide; [ChemIDplus]

Category

Fungicides

Description

Solid; [IUCLID]

Sources/Uses

Used as a chemical intermediate for the fungicides Captan and Captafol; [HSDB]

Comments

Emergency treatment: "Phthalimide fungicides"; Captan and Captafol are of "low order of acute toxicity." Both are skin sensitizers that in animal experiments can cause cancer and liver, reproductive, and developmental toxicity. [HSDB] Mildly irritating to rabbit skin; Teratogenic effects observed in hamsters dosed by gavage at 1,000 mg/kg; No teratogenic effects noted in rabbits but minor increase in resorptions observed; No evidence of mutagenicity; [IUCLID] See "Captan" and "Captafol."

Exposure Assessment
Explanatory Notes

Flash point = 190 deg C; [eChemPortal: IUCLID]

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