Agent Name

1,2,3-Trichloropropene

CAS Number

96-19-5

Formula

C3-H3-Cl3

Major Category

Other Classes

Synonyms

1,2,3-Trichlor-1-propene; 1,2,3-Trichloro-1-propene; 1-Propene, 1,2,3-trichloro-; 2,3-Dichloroallyl chloride; Propene, 1,2,3-trichloro-; [ChemIDplus]

Category

Halogenated Aliphatics, Unsaturated

Description

Amber liquid; [CAMEO]

Sources/Uses

Used as a chemical intermediate; [HSDB]

Comments

Caused somnolence in rats at 36 ppm for 6 hours; [RTECS] External application to rabbit eyes scored 5 on a scale of 1-10 after 24 hours (moderate irritation); Observations in three month rodent inhalation study include eye and upper respiratory tract irritation and increased liver enzymes; No significant gross or histopathological effects observed in 13 week inhalation study with rats; A ten week inhalation study with rats produced no evidence of reproductive or developmental toxicity; [HSDB] May cause irritation or burns; [CAMEO] An irritant that may cause burns; [MSDSonline]

Exposure Assessment
Vapor Pressure

4.4 mm Hg

Lethal Concentration

LCLo (rat) = 500 ppm/4h

Explanatory Notes

Flash point = 85 deg C; [HSDB]

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Diseases

Occupational diseases associated with exposure to this agent: