Agent Name

1,2-Dibromopropane

CAS Number

78-75-1

Formula

C3-H6-Br2

Major Category

Other Classes

Synonyms

2,3-Dibromopropane; Propylene dibromide; Propane, 1,2-dibromo-; [ChemIDplus]

Category

Halogenated Aliphatics, Saturated

Description

Colorless liquid; [Merck Index]

Sources/Uses

Used as a research chemical; [HSDB]

Comments

Increased liver enzymes in feeding studies of mice; Some evidence of mutagenicity; Emergency medical treatment: see "2-Bromopropane." [HSDB] High concentrations may have irritating and narcotic effects; [CAMEO] A mutagen; Effects in high-dose animal studies include fatty liver degeneration and acute renal failure; [RTECS]

Exposure Assessment
Vapor Pressure

7.84 mm Hg

Lethal Concentration

LC50 (rat) = 12,000 mg/m3/4h

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: