Agent Name

1,2-Dichloro-1,1,2-trifluoroethane

CAS Number

354-23-4

Formula

C2-H-Cl2-F3

Major Category

Solvents

Synonyms

1,1,2-Trifluoro-1,2-dichloroethane; CFC 123a; F 123a; HCFC 123a; R 123a; Ethane, 1,2-dichloro-1,1,2-trifluoro-; [ChemIDplus]

Category

Chlorofluorocarbons

Description

Colorless gas; [CAMEO] Colorless liquid; [MSDSonline]

Sources/Uses

HCFCs: Used as refrigerants, blowing agents, cleaning agents, and fire extinguishing agents (CFC alternatives); [HSDB]

Comments

In concentrations >18,500 ppm, acts as general anesthetic in rat inhalation studies; [RTECS] May cause irritation; Inhalation of high concentrations can cause CNS depression; Evaporating liquid can cause frostbite; [MSDSonline] See "CHLOROFLUOROCARBONS."

Exposure Assessment
Vapor Pressure

620 mm Hg

Lethal Concentration

LCLo (mice) = 150,000 ppm/2 min

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: