Agent Name

3,3'-Dichlorobenzidine

CAS Number

91-94-1

Formula

C12-H10-Cl2-N2

Major Category

Nitrogen Compounds

Synonyms

(1,1'-Biphenyl)-4,4'-diamine, 3,3'-dichloro-; 3,3'-Dichlorbenzidin [Czech]; 3,3'-Dichloro-(1,1'-biphenyl)-4,4'-diamine; 3,3'-Dichloro-4,4'-biphenyldiamine; 3,3'-Dichloro-4,4'-diamino(1,1-biphenyl); 3,3'-Dichloro-4,4'-diaminobiphenyl; 3,3'-Dichloro-4,4'-diaminodiphenyl; 3,3'-Dichloro-p,p'-bianiline; 3,3'-Dichlorobenzidin [Czech]; 3,3'-Dichlorobenzidina [Spanish]; 3,3'-Dichlorobenzidine; 3,3'-Dichlorobenzidine base; 3,3'-Dichlorobiphenyl-4,4'-diamine; 4'-Amino-3,3'-dichloro(1,1'-biphenyl)-4-ylamine; 4,4'-Diamino-3,3'-dichlorobiphenyl; 4,4'-Diamino-3,3'-dichlorodiphenyl; Benzidine, 3,3'-dichloro-; C.I. 23060; CI 23060; Curithane C126; Dichlorobenzidine base; o,o'-Dichlorobenzidine; ortho,ortho'-Dichlorobenzidine; [ChemIDplus]

Category

Benzidine and Derivatives

Description

Gray to purple, crystalline solid; [NIOSH]

Sources/Uses

Used as an intermediate in the manufacture of azo dyes and benzidine yellow pigments; also used as a curing agent for urethane plastics; [ACGIH]

Comments

Liver injury occurs in animals in subchronic feeding studies. [ACGIH] A skin, eye, and respiratory tract irritant; [ICSC] See "3,3'-Dichlorobenzidine dihydrochloride."

Restricted

Carcinogen--See 29CFR1910.1003 (Code of Federal Regulations).

Reference Link

ATSDR - ToxFAQs - 3,3'-Dichlorobenzidine

Exposure Assessment
Skin Designation (ACGIH)

Yes

Explanatory Notes

Carcinogen--No TLV;

Half Life

No reports found; [TDR, p. 486]

Reference Link

ICSC: 3,3'-Dichlorobenzidine

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

IARC Carcinogen

Possible Carcinogen

NTP Carcinogen

Anticipated Human Carcinogen

ACGIH Carcinogen

Confirmed Animal

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: