Agent Name

Bis(chloromethyl) ether

CAS Number

542-88-1

Formula

C2-H4-Cl2-O

Major Category

Other Classes

Synonyms

1,1'-Dichlorodimethyl ether; Chloro(chloromethoxy)methane; Chloromethyl ether; Dichlordimethylaether [German]; Dichloromethyl ether, symmetrical; Dimethyl-1,1'-dichloroether; Ether, bis(chloromethyl); Methane, oxybis(chloro-; Oxybis(chloromethane); sym-Dichloro-dimethyl ether; sym-Dichloromethyl ether; [ChemIDplus] UN2249

Category

Halogenated Ethers

Description

Colorless liquid with a suffocating odor; [NIOSH]

Sources/Uses

Used in the past to make polymers, resins, and textiles; Currently, only small amounts are used in enclosed systems in the chemical industry. [ACGIH]

Comments

A corrosive substance that can cause pulmonary edema; [ICSC]

Restricted

Regulated as a carcinogen; See 29CFR1910.1003;

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

0.001 ppm

Vapor Pressure

30 mm Hg

Lethal Concentration

LC50 (rat) = 7 ppm/7h

Explanatory Notes

Flash point < 19 deg C;

Half Life

No reports found; [TDR, p. 191]

Reference Link

ATSDR - ToxFAQs - Bis(chloromethyl) Ether

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

IARC Carcinogen

Known Carcinogen

NTP Carcinogen

Human Carcinogen

ACGIH Carcinogen

Confirmed Human

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: