Agent Name

4-Aminodiphenyl

CAS Number

92-67-1

Formula

C12-H11-N

Major Category

Nitrogen Compounds

Synonyms

1,1'-Biphenyl)-4-amine; 4-Amino-1,1'-biphenyl; 4-Aminobifenyl [Czech]; 4-Aminobiphenyl; 4-Aminodifenil [Spanish]; 4-Aminodiphenyl; 4-Bifenylamin [Czech]; 4-Biphenylamine; 4-Biphenylylamine; 4-Phenylaniline; Aniline, p-phenyl-; Biphenylamine; Paraaminodiphenyl; Xenylamin [Czech]; Xenylamine; p-Aminobiphenyl; p-Aminodiphenyl; p-Biphenylamine; p-Phenylaniline; p-Xenylamine; [ChemIDplus]

Category

Amines, Polyaromatic

Description

Colorless crystals with a floral odor; Note: Turns purple on contact with air; [NIOSH]

Sources/Uses

No longer produced commercially; [ACGIH]

Comments

A potential occupational carcinogen that can cause hemorrhagic cystitis and methemoglobinemia; [CAMEO] An eye irritant; [ICSC] Bladder cancer--regulated as a carcinogen by OSHA; see "Carcinogens" in 29 CFR 1910.1003;

Restricted

See 29CFR1910.1003 (Code of Federal Regulations pertaining to the manufacturing, processing, repackaging, releasing, handling, and storing of this carcinogen).

Reference Link

NIOSH Occupational Health Guidelines for Chemical Hazards: 4-Aminodiphenyl

Exposure Assessment
Skin Designation (ACGIH)

Yes

Vapor Pressure

0.000117 mm Hg

Explanatory Notes

Carcinogen--No TLV; Flash point > 235 deg F;

Half Life

No reports found; [TDR, p. 83]

Adverse Effects
Methemoglobinemia

Methemoglobinemia, Secondary

Dermatotoxin

Skin Burns

IARC Carcinogen

Known Carcinogen

NTP Carcinogen

Human Carcinogen

ACGIH Carcinogen

Confirmed Human

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: