Agent Name

1,3-Dichloro-2-butene

CAS Number

926-57-8

Formula

C4-H6-Cl2

Major Category

Other Classes

Synonyms

1,3-Dichlorobutylene; 2-Butene, 1,3-dichloro-; [ChemIDplus] 1,3-DCB; [SIDS UNEP]

Category

Halogenated Aliphatics, Unsaturated

Description

Clear to straw-colored liquid; [HSDB] Colorless liquid; [MSDSonline]

Sources/Uses

Used in the pesticide DDB and as an intermediate in organic synthesis; [HSDB] Commercially manufactured and consumed solely as on-site intermediate in the production of 2,3-dichloro-1,3-butadiene (comonomer for polychloroprene synthetic rubber); [SIDS UNEP]

Comments

A skin, eye, and respiratory tract irritant; Exposure to high vapor concentrations can cause severe respiratory distress, lacrimation, and possibly coma; Inhalation of low concentrations may cause CNS depression; May cause kidney, liver, and heart injury; Emergency medical treatment: "chlorinated hydrocarbon insecticides"; [HSDB] Corrosive to rabbit skin; Occupational exposures demonstrate irritation and corrosive injuries to skin, with the vapor causes eye and respiratory tract irritation; A possible carcinogen based on the structural analog 1,3-Dichloropropene (DCP) CAS # 542-75-6, which has an IARC classification of possible human carcinogen; No evidence of reproductive or developmental toxicity in rats or rabbits; [SIDS UNEP]

Exposure Assessment
Vapor Pressure

12.6 mm Hg

Lethal Concentration

LC50 (rat) = 3,930 mg/m3/4h

Explanatory Notes

Flash point = 27 deg C; [HSDB]

Adverse Effects
Lacrimator

Yes

Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Processes

Industrial Processes with risk of exposure: