Agent Name

1,4-Benzenediamine, N-(1,3-dimethylbutyl)-N'-phenyl-

CAS Number

793-24-8

Formula

C18-H24-N2

Major Category

Nitrogen Compounds

Synonyms

6PPD; Antage 6C; Antioxidant 4020; Antioxidant CD 13; Antozite 67; Antozite 67F; CD 13; DBDA; DMBPD; Diafen 13; Diafen FDMB; Dusantox 6PPD; Flexzone 7F; Flexzone 7L; Forte 6C; N-(1,3-Dimethylbutyl)-N'-phenyl-1,4-phenylenediamine; N-(1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine; N-1,3-Dimethylbutyl-N'-phenyl-p-phenylendiamine; N-Phenyl-N'-(1,3-dimethyl butyl)-para-phenylenediamine; N-Phenyl-N'-(1,3-dimethylbutyl)-p-phenylenediamine; Nocrac 6C; Nocrane 6C; Nocrane 7 L; Ozonon 6C; Permanax 120; Permanax 6PPD; Santoflex 13; Santoflex 13F; Santoflex 6PPD; UOP 562; UOP 588; Vulkanox 4020; Wingstay 300; p-Phenylenediamine, N-(1,3-dimethylbutyl)-N'-phenyl-; [ChemIDplus] UN3077

Category

Amines, Polyaromatic

Description

Dark violet solid; [HSDB] Brown to violet solid; Turns dark brown on light exposure; [ICSC]

Sources/Uses

Used as an antiozonant and antioxidant for butadiene rubber, nitrile-butadiene rubber, styrene-butadiene rubber, and synthetic isoprene rubber; [HSDB]

Comments

Reports of skin sensitization in employees in tire and rubber industries; Not mutagenic in four strains of Salmonella and not clastogenic in mice bone marrow cells; Emergency treatment: "Paraphenylenediamine"; In sensitized individuals, paraphenylenediamine may cause allergic contact dermatitis following application as a hair dye and asthma following inhalation; Following ingestion, can cause angioneurotic edema, methemoglobinemia, acute tubular necrosis, and hepatotoxicity; An adult died after ingestion of 3 grams of p-phenylenediamine; Another adult who ingested 1800 mg developed angioneurotic edema and acute renal failure; [HSDB] A mild skin and eye irritant; May cause skin sensitization; [ICSC] May cause skin irritation and sensitization; [CAMEO] A mild skin and eye irritant; Likely a skin sensitizer based on animal studies and positive patch test results in volunteers exposed to rubber formulations; [CHEMINFO] See "p-Phenylenediamine."

Reference Link

OECD SIDS: N-(1,3-Dimethylbutyl)-N-phenyl-1,4-phenylenediamine - 2004

Exposure Assessment
MAK

2 mg/m3, inhalable fraction

Vapor Pressure

5.0E-6 mm Hg

Explanatory Notes

Flash point = 204 deg C; [CAMEO] The Guide in the Emergency Response Guidebook is for "Environmentally hazardous substances, solid, n.o.s."

Adverse Effects
Skin Sensitizer

Yes

Hepatotoxin

Hepatotoxin, Secondary

Methemoglobinemia

Methemoglobinemia, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: