Agent Name

Thiosemicarbazide

Alternative Name

1-Amino-2-thiourea

CAS Number

79-19-6

Formula

C-H5-N3-S

Major Category

Nitrogen Compounds

Synonyms

1-Amino-2-thiourea; 1-Aminothiourea; 2-Thiosemicarbazide; 3-Thiosemicarbazide; Aminothio-urea; Hydrazinecarbothioamide; Isothiosemicarbazide; Isothiosemicarbazide (VAN); N-Aminothiourea; Semicarbazide, 3-thio-; Semicarbazide, thio-; TSC; TSZ; Thiocarbamoylhydrazine; Thiocarbamylhydrazine; [ChemIDplus] UN2811

Category

Thiourea Compounds

Description

White, odorless solid; [Hawley] Off-white crystalline powder; [Alfa Aesar MSDS]

Sources/Uses

Used as a reagent for ketones and detection of metals, rodenticide, and chemical intermediate; Also used in photography; [HSDB] Effective for controlling bacterial leaf blight in rice: [CAMEO]

Comments

May cause irritation, goiter, bone marrow depression, hyperglycemia, CNS excitation, seizures, and pulmonary edema after ingestion; A GABA synthesis inhibitor in experimental animals; [HSDB] Causes convulsions in lethal-dose studies of guinea pigs, mice, and cats (oral, ocular, intravenous, and intraperitoneal routes); [RTECS] An irritant; [Alfa Aesar MSDS]

Restricted

Not registered as a pesticide for use in the US; [CAMEO]

Exposure Assessment
Vapor Pressure

0.33 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Toxic solid, organic, n.o.s."

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Related Information in HazMap
Processes

Industrial Processes with risk of exposure: