Agent Name

1-Aziridineethanol

CAS Number

1072-52-2

Formula

C4-H9-N-O

Major Category

Nitrogen Compounds

Synonyms

1-(2-Hydroxyethyl)ethylenimine; 1-Azirdineethanol; 2-(1-Aziridinyl)ethanol; 2-Hydroxy-1-ethylaziridine; Ethanol, 2-(1-aziridinyl)-; Hydroxyethylethyleneimine; N-(2-Hydroxyethyl)aziridine; N-(2-Hydroxyethyl)ethyleneimine; N-(2-Hydroxyethyl)ethylenimine; N-(Hydroxyethyl)ethyleneimine; N-(beta-Hydroxyethyl)aziridine; N-Hydroxyethyl ethylene imine; beta-Hydroxy-1-ethylaziridine; [ChemIDplus]

Category

Other Nitrogen Compounds

Description

Colorless liquid; [Hawley] Colorless or yellow liquid; [CAMEO]

Sources/Uses

Used as a chemical intermediate and chemical modifier for latex polymers, coatings, textile resins, starches, paper, wood, and cellulose fibers; [HSDB]

Comments

Single oral doses (125-1000 mg/kg) to rats caused liver necrosis; [HSDB] Hydrolyzes forming diethanolamine; A skin, eye, nose and mucous membrane irritant; May cause liver injury; [CAMEO] Caused severe irritation to eyes and skin of rabbits; [RTECS] Causes burns; Highly toxic through skin absorption; An upper respiratory tract irritant; Toxic if swallowed; [Aldrich MSDS]

Exposure Assessment
Vapor Pressure

0.49 mm Hg

Lethal Concentration

LC (rat) > 850 ppm/8h

Explanatory Notes

Flash point = 85 deg C; [Hawley]

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

IARC Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Processes

Industrial Processes with risk of exposure: