Agent Name

1-Bromobutane

Alternative Name

n-Butyl bromide

CAS Number

109-65-9

Formula

C4-H9-Br

Major Category

Other Classes

Synonyms

1-Butyl bromide; Butyl bromide; Butane, 1-bromo-; n-Butyl bromide; [ChemIDplus] UN1126

Category

Halogenated Aliphatics, Saturated

Description

Colorless to pale straw-colored liquid; [HSDB] Colorless liquid; [MSDSonline]

Sources/Uses

Used as an alkylating agent and in the preparation of drugs; [HSDB]

Comments

Flammable liquid; [Hawley] Irritating to the skin of mice and the eyes of rabbits; Did not induce sensitization by application to the ear of mice and determined by local lymph node assay; Degeneration of vacuolar liver cells was observed in 28 day feeding study with rats; Evidence of mutagenicity in Salmonella typhimurium and Chinese hamster cells; [HSDB] A skin, eye, nose, throat, and respiratory tract irritant; [CAMEO] Causes somnolence and ataxia in lethal-dose feeding studies of rats; [RTECS]

Exposure Assessment
Vapor Pressure

42 mm Hg

Lethal Concentration

LC50 (rat) = 47,000 mg/m3/2h

Explanatory Notes

Flash point = 18 deg C; [HSDB]

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Diseases

Occupational diseases associated with exposure to this agent: