Agent Name

1-Chloro-1,1-difluoroethane

CAS Number

75-68-3

Formula

C2-H3-Cl-F2

Major Category

Solvents

Synonyms

Chlorofluorocarbon 142b; Ethane, 1-chloro-1,1-difluoro-; Propellant 142b; 1,1-Difluoro-1-chloroethane; 1-Chloro-1,1-difluoroethane; CFC 142b; Chloroethylidene fluoride; Difluoro-1-chloroethane; FC142b; Fluorocarbon 142b; Fluorocarbon FC142b; Freon 142; Freon 142b; Genetron 101; Genetron 142b; Gentron 142B; Gentron 142b; Hydrochlorofluorocarbon 142b; Isotron 142b; Monochlorodifluoroethane; R-142b; HCFC-142b; [ChemIDplus] UN2517

Category

Chlorofluorocarbons

Description

A colorless gas shipped as a liquid under its own vapor pressure; [CAMEO]

Sources/Uses

Used as an aerosol propellant, blowing agent, refrigerant, and chemical intermediate; [HSDB] Used as a solvent; [Hawley] Used mainly as an intermediate with limited use as an aerosol propellant and possible use as a blowing agent and refrigerant; [AIHA]

Comments

In confined space spill, may displace air and act as simple asphyxiant; Evaporating liquid can cause frostbite; At high concentrations, may sensitize heart to arrhythmias; [ICSC] May cause irritation; May cause rapid suffocation; [MSDSonline] It has anesthetic effects at high concentrations; Threshold for cardiac sensitization in rats is 50,000 ppm; [AIHA]

Exposure Assessment
MAK

1000 ppm

WEEL

1000 ppm

Lethal Concentration

LC50 (mice) = 447,000 ppm/2h;

Flammability (NFPA)

4: Burns readily

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Other Poison

Simple Asphyxiant

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: