Agent Name

1-Chloropropane

Alternative Name

Propyl chloride

CAS Number

540-54-5

Formula

C3-H7-Cl

Major Category

Other Classes

Synonyms

n-Propyl chloride; Propane, 1-chloro-; Propyl chloride; [ChemIDplus] UN1278

Category

Halogenated Aliphatics, Saturated

Description

Colorless liquid; [Merck Index]

Sources/Uses

Used as a chemical intermediate for n-Propylamine; Has been studied for use as an anesthetic and parasiticidal drug; [HSDB]

Comments

Flammable liquid; [Hawley] Irritant and CNS depressant; External application to rabbit eyes scored 2 on a scale of 1-10 (10 being most severe) for degree of injury after 24 hours; Observations in 4-day inhalation study with rats include minor alveolar hemorrhage and focal necrosis of the liver; Emergency medical treatment: see "Ethyl chloride." [HSDB] An eye, nose, and throat irritant; May cause CNS depression in high concentrations; [CAMEO]

Restricted

No known current commercial production in the US; [HSDB]

Exposure Assessment
Vapor Pressure

345 mm Hg

Explanatory Notes

Flash point = -17.7 deg C; [Hawley]

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: