Agent Name

Ethanolamine

Alternative Name

2-Aminoethanol

CAS Number

141-43-5

Formula

C2-H7-N-O

Major Category

Nitrogen Compounds

Synonyms

1-Amino-2-hydroxyethane; 2-Amino-1-ethanol; 2-Aminoaethanol [German]; 2-Aminoetanolo [Italian]; 2-Aminoethanol; 2-Hydroxyethanamine; 2-Hydroxyethylamine; Aethanolamin [German]; Aminoethanol; Colamine; Etanolamina [Italian]; Ethanol, 2-amino-; Ethanolamine; Ethylolamine; Glycinol; Glycinol (monoethanolamine); Kolamin [Czech]; MEA (alcohol); Monoaethanolamin [German]; Monoethanolamine; Olamine; Thiofaco M-50; beta-Aminoethyl alcohol; beta-Hydroxyethylamine; [ChemIDplus] UN2491

Category

Ethanolamines

Description

Colorless, viscous liquid or solid (below 51 degrees F) with an unpleasant, ammonia-like odor; [NIOSH]

Sources/Uses

Used as a scavenger for CO2 and H2S in natural gas; used in the synthesis of surface active agents, hair waving agents, hide softeners, agricultural chemicals, and antibiotics; [Merck Index, # 3727] Used in soaps, cosmetics, polishes, paints, cutting oils, and textile processing; [HSDB] Used in photography (color developing bath); [www.ci.tucson.az.us/arthazards/medium.html]

Comments

Liquid causes first degree burns on short exposure; [CHRIS] Ethanolamine is a skin irritant. [Quick CPC] Occupational asthma reported in hairdressers; [Malo] Toxic to the liver in subchronic inhalation studies of animals; [ACGIH] It is an irritant, but allergic contact dermatitis has been reported. [Kanerva, p. 1817] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; Can cause skin sensitization; [ICSC] Danger of skin sensitization; [MAK]

Reference Link

Allergic contact dermatitis from mono-, di- and triethanolamine

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

3 ppm

STEL (ACGIH)

6 ppm

PEL (OSHA)

3 ppm

MAK

0.2 ppm

IDLH (NIOSH)

30 ppm

Excerpts from Documentation for IDLHs

Other animal data: Cats exposed for 2 hours to vapors of ethanolamine at concentrations reaching 970 ppm displayed vomiting tendencies; mice had no adverse effects from the same exposures [Sidorov et al. 1968]. A single 8hour exposure to "concentrated vapors" did not kill any of six rats [UCC 1970]. Guinea pigs survived a 15minute exposure to ethanolamine at 193 ppm [Treon et al. 1957].

Vapor Pressure

0.4 mm Hg

Odor Threshold Low

2.6 ppm

Odor Threshold High

5 ppm

Lethal Concentration

LC50 (mice) > 2,420mg/m3/2H

Explanatory Notes

Odor threshold (detect at 2.6 ppm and recognize at 5 ppm) from CHEMINFO; Flash point = 86 deg C;

Reference Link

ICSC: Ethanolamine

Adverse Effects
Skin Sensitizer

Yes

Asthma

Yes

Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: