Agent Name

Ethanolamine

Alternative Name

2-Aminoethanol

CAS Number

141-43-5

Formula

C2-H7-N-O

Major Category

Nitrogen Compounds

Synonyms

1-Amino-2-hydroxyethane; 2-Amino-1-ethanol; 2-Aminoaethanol [German]; 2-Aminoetanolo [Italian]; 2-Aminoethanol; 2-Hydroxyethanamine; 2-Hydroxyethylamine; Aethanolamin [German]; Aminoethanol; Colamine; Etanolamina [Italian]; Ethanol, 2-amino-; Ethanolamine; Ethylolamine; Glycinol; Glycinol (monoethanolamine); Kolamin [Czech]; MEA (alcohol); Monoaethanolamin [German]; Monoethanolamine; Olamine; Thiofaco M-50; beta-Aminoethyl alcohol; beta-Hydroxyethylamine; [ChemIDplus] UN2491

Category

Ethanolamines

Description

Colorless, viscous liquid or solid (below 51 degrees F) with an unpleasant, ammonia-like odor; [NIOSH]

Sources/Uses

Used as a scavenger for CO2 and H2S in natural gas; used in the synthesis of surface active agents, hair waving agents, hide softeners, agricultural chemicals, and antibiotics; [Merck Index, # 3727] Used in soaps, cosmetics, polishes, paints, cutting oils, and textile processing; [HSDB] Used in photography (color developing bath); [www.ci.tucson.az.us/arthazards/medium.html]

Comments

Liquid causes first degree burns on short exposure; [CHRIS] Ethanolamine is a skin irritant. [Quick CPC] Occupational asthma reported in hairdressers; [Malo] Toxic to the liver in subchronic inhalation studies of animals; [ACGIH] It is an irritant, but allergic contact dermatitis has been reported. [Kanerva, p. 1817] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; Can cause skin sensitization; [ICSC]

Reference Link

Allergic contact dermatitis from mono-, di- and triethanolamine

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

3 ppm

STEL (ACGIH)

6 ppm

PEL (OSHA)

3 ppm

MAK

0.2 ppm

IDLH (NIOSH)

30 ppm

Excerpts from Documentation for IDLHs

Other animal data: Cats exposed for 2 hours to vapors of ethanolamine at concentrations reaching 970 ppm displayed vomiting tendencies; mice had no adverse effects from the same exposures [Sidorov et al. 1968]. A single 8hour exposure to "concentrated vapors" did not kill any of six rats [UCC 1970]. Guinea pigs survived a 15minute exposure to ethanolamine at 193 ppm [Treon et al. 1957].

Vapor Pressure

0.4 mm Hg

Odor Threshold Low

2.6 ppm

Odor Threshold High

5 ppm

Lethal Concentration

LC50 (mice) > 2,420mg/m3/2H

Explanatory Notes

Odor threshold (detect at 2.6 ppm and recognize at 5 ppm) from CHEMINFO; Flash point = 86 deg C;

Reference Link

ICSC: Ethanolamine

Flammability (NFPA)

2: High ambient temperature required

Adverse Effects
Skin Sensitizer

Yes

Asthma

Yes

Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: