Agent Name

1-Fluoro-2,4-dinitrobenzene

CAS Number

70-34-8

Formula

C6-H3-F-N2-O4

Major Category

Nitrogen Compounds

Synonyms

2,4-DNFB; 2,4-Dinitro-1-fluorobenzene; 2,4-Dinitrobenzene fluoride; 2,4-Dinitrobenzenefluoride; 2,4-Dinitrofluorobenzene; 2,4-Dinitrophenyl fluoride; Benzene, 1-fluoro-2,4-dinitro-; Benzene, 2,4-dinitro-1-fluoro-; DFB (VAN); DNFB; Dinitrofluorobenzene; FDNB; Fluoro-2,4-dinitrobenzene; Fluorodinitrobenzene (VAN); [ChemIDplus] UN1597

Category

Nitros, Aromatic

Description

Pale yellow solid; [Merck Index] Yellow low melting crystalline solid; mp = 23-26 deg C; [MSDSonline]

Sources/Uses

Used as a reagent (labeling terminal amino acid groups and modified Wohl degradations of aldoses) and hapten; [Merck Index]

Comments

A mutagen and sensitizer; [RTECS] Emergency treatment: Methemoglobinemia; [HSDB] A strong irritant and vesicant; [HSDB] A skin, eye, and mucous membrane irritant; "This chemical is highly toxic, a powerful irritant, and causes blistering. It caused allergic reactions and dermatitis by skin contact or inhalation. It can be absorbed through the skin." [CAMEO] A powerful irritant and vesicant; May be absorbed through skin; May cause skin and respiratory sensitization after prolonged contact; [MSDSonline]

Exposure Assessment
Vapor Pressure

0.0024 mm Hg

Explanatory Notes

Flash point > 113 deg C; [CAMEO] The Guide in the Emergency Response Guidebook is for "Dinitrobenzenes."

Adverse Effects
Skin Sensitizer

Yes

Methemoglobinemia

Methemoglobinemia, Secondary

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: