Agent Name

2-Aminopyridine

CAS Number

504-29-0

Formula

C5-H6-N2

Major Category

Nitrogen Compounds

Synonyms

2-Aminopyridine; alpha-Aminopyridine; 1,2-Dihydro-2-iminopyridine; 2-Aminopryidine; 2-Aminopyridine; 2-Pyridinamine; 2-Pyridylamine; Amino-2 pyridine; alpha-Aminopyridine; alpha-Pyridinamine; alpha-Pyridylamine; o-Aminopyridine; UN2671; [ChemIDplus]

Category

Pyridines

Description

White powder, leaflets, or crystals with a characteristic odor; [NIOSH]

Sources/Uses

Used to manufacture drugs and dyes; [Merck Index # 473]

Comments

A chemical plant worker died after a spill which contaminated his clothing. He did not remove his clothing, and symptoms began about 2 hours after the exposure with headache and dizziness followed by respiratory distress and convulsions. [ACGIH] See "Pyridine."

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

0.5 ppm

PEL (OSHA)

0.5 ppm

IDLH (NIOSH)

5 ppm

Excerpts from Documentation for IDLHs

Very little quantitative data are available on which to base an IDLH for 2-aminopyridine. The chosen IDLH is based on the statement by ACGIH [1971] that a 5-hour exposure to about 5 ppm produced headache, increased blood pressure, and nausea in a worker [Watrous and Schulz 1950].

Vapor Pressure

0.09 mm Hg

Explanatory Notes

Flash point = 198 deg F; [CAMEO]

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: