Agent Name

1-Naphthol

Alternative Name

alpha-Naphthol

CAS Number

90-15-3

Formula

C10-H8-O

Major Category

Other Classes

Synonyms

alpha-Naphthol; 1-Hydroxynaphthalene; 1-Naphthalenol; BASF Ursol ERN; C.I. 76605; C.I. Oxidation Base 33; CI 76605; CI Oxidation Base 33; Durafur Developer D; Fouramine ERN; Fourrine 99; Fourrine ERN; Furro ER; Nako TRB; Tertral ERN; Ursol ERN; Zoba ERN; alpha-Hydroxynaphthalene; alpha-Naphthol; [ChemIDplus] UN2811

Category

Naphthols

Description

Colorless or yellow solid; [Hawley] Darkens on exposure to light; [Merck Index] Colorless crystalline solid; [MSDSonline]

Sources/Uses

Used to make dyes, intermediates, synthetic perfumes, agrochemicals, drugs, and rubber antioxidants; [HSDB] Used in organic synthesis; [Hawley] Used in photography; in the hide tanning process; in pyrotechnics for black smoke; [IUCLID]

Comments

Toxic by ingestion or skin absorption; [Hawley] A skin and respiratory tract irritant; May cause severe damage to eyes; [eChemPortal: ESIS] An irritant; A severe eye irritant which may cause serious injury; May be absorbed through skin; May cause kidney injury; Effects in high-dose animal studies include impaired liver function tests and CNS injury; [MSDSonline] May cause skin irritation and eye injury; [Ullmann] Toxic by ingestion; Alpha isomer is more toxic than beta isomer; Lethal human dose = 50-500 mg/kg (beta-Naphthol); Acute effects include liver and kidney injury, hemolytic anemia, and lens opacities; [HSDB]

Exposure Assessment
Vapor Pressure

0.000274 mm Hg

Lethal Concentration

LC50 (rat) > 420 mg/m3/1h

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Toxic solid, organic, n.o.s."

Adverse Effects
Nephrotoxin

Yes

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Processes

Industrial Processes with risk of exposure: